Experts focus on function to develop resilient microbial communities for biotechnologies

March 3, 2016, Pacific Northwest National Laboratory

Resilience is an important concept these days, in everything from human communities restoring order after natural disasters to microbial communities recovering from a chemical spill. However, there's no agreement on how resilience should be defined and measured. One scientific body identified 47 definitions of resilience used in diverse areas, including engineering, ecology, sociology, economics, and psychology. Yet, understanding resilience in microbial communities is a critical component to engineering them for biotechnologies or predicting how they will respond to a changing environment. These communities must be able to recover quickly from an environmental change so their function is stable over time.

Now a group of Pacific Northwest National Laboratory computational biologists and microbiologists has proposed a way to define resilience in microbial communities that unites ecologists and engineers. Their efforts were recently featured in Frontiers in Microbiology.

"We believe that resilience in microbial communities is best defined as the rate of recovery of a given function of interest to the researcher," said Dr. Stephen Lindemann, the PNNL microbiologist who led the team. "Focusing on the system's fundamental characteristics in response to a specific change in the environment not only allows us to compare resilience of a function between communities, but also provides a deeper understanding of community properties. Using this definition, we propose that resilience comes from within a microbial community-regardless of the environment it lives in."

They may be tiny, but microorganisms collectively exceed the mass of all other plants and animals on the planet. They control the carbon and energy cycles on the planet, and scientists are beginning to appreciate their role in shaping human health and physiology. These little wonders are also being studied as a potential means to capture renewable energy. Understanding the processes that govern how microbial communities respond to changes in their environment is critical to ecologists concerned with predicting the effects on ecosystems from climate change or volcanic eruptions and to engineers designing communities for stable biotechnology processes.

"To design the best system, we must develop rational methods to quantify microbial community resilience and be able to predict approaching tipping points," Lindemann said.

Seeking an integrated concept of resilience applicable to all microbial communities, the scientists compared previous resilience studies from an engineering and ecological standpoint. Consistently, they found that changes in the microbes' environment might result in changes to the community's composition or size but maintained critical functions. Understanding how these functions will respond to changes in the environment is of central importance to both ecologists and engineers.

PNNL scientists plan to identify fundamental mechanisms responsible for the of both simple and highly complex microbial communities. Understanding these mechanisms will significantly advance the capability to design, predict the behavior of, and control , whether in natural ecosystems or bioengineered systems.

Explore further: Bacteria's conflicts fuel synthetic ecology research

More information: Hyun-Seob Song et al. Integrating Ecological and Engineering Concepts of Resilience in Microbial Communities, Frontiers in Microbiology (2015). DOI: 10.3389/fmicb.2015.01298

Related Stories

Bacteria's conflicts fuel synthetic ecology research

August 18, 2015

A common characteristic in mixed populations of microbes is that some bacteria, the "cooperators," dominate over others, the "cheaters." Cheaters use resources cooperators make and share. The result? The community suffers ...

Tracking microbial mat formation in Yellowstone

February 11, 2016

Researchers determined the contributions of different microbes toward the establishment of microbial mat communities in the hot and acidic environments of the Yellowstone Hot Springs.

Recommended for you

Cells lacking nuclei struggle to move in 3-D environments

January 20, 2018

University of North Carolina Lineberger Comprehensive Cancer Center researchers have revealed new details of how the physical properties of the nucleus influence how cells can move around different environments - such as ...

Microbial communities demonstrate high turnover

January 19, 2018

When Mark Twain famously said "If you don't like the weather in New England, just wait a few minutes," he probably didn't anticipate MIT researchers would apply his remark to their microbial research. But a new study does ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.