Nucleic Acids Research is a peer-reviewed scientific journal published by Oxford University Press. It covers research on nucleic acids, such as DNA and RNA, and related work. Some of its content is available under an open access license. According to the Journal Citation Reports, the journal s 2010 impact factor is 7.836. The journal publishes two yearly special issues, one dedicated to biological databases, published in January since 1993 and the other on biological web servers, published in July since 2003.
If everything is to run smoothly in living cells, the genetic information must be correct. But unfortunately, errors in the DNA accumulate over time due to mutations. Land plants have developed a peculiar correction mode: ...
Cell & Microbiology
Sep 19, 2022
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602
One of the most hotly contested issues in biology, or at least in mitochondrial biology, is determining which proteins can get into mitochondria. Having this kind of access essentially means a protein maintains a residence ...
A team led by a Baylor University researcher has published a breakthrough article that provides a better understanding of the dynamic process by which sunlight-induced DNA damage is recognized by the molecular repair machinery ...
Molecular & Computational biology
Jul 14, 2019
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343
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development ...
Cell & Microbiology
Apr 18, 2024
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20
CRISPR/Cas systems have undergone tremendous advancement in the past decade. These precise genome editing tools have applications ranging from transgenic crop development to gene therapy and beyond. And with their recent ...
Biotechnology
Feb 13, 2024
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63
A recent study from the University of Eastern Finland shows that genetic variation determines chromatin accessibility and the binding of transcription factors. Chromatin consists of DNA and proteins attached to it. The density ...
Molecular & Computational biology
Jan 22, 2024
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5
Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact ...
Molecular & Computational biology
Jan 22, 2024
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36
A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering. The new technology, developed by researchers ...
Biotechnology
Jan 16, 2024
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77
The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team led by Christian Seiser from MedUni Vienna's Center ...
Molecular & Computational biology
Jan 11, 2024
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213
Modern pharmaceutical research generates large amounts of data faster than ever before. To analyze and evaluate this data, it is collected and structured in extensive databases and thus provides the basis for the development ...
Cell & Microbiology
Jan 9, 2024
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38
