Researchers identify drug compounds that can reduce prion protein levels in infected cells
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Biochemistry
May 15, 2024
0
30
Pathogens are nothing if not adaptable, and their ability to protect themselves against antibiotics increasingly poses a public health concern. A research team led by Los Alamos National Laboratory has used machine learning, ...
Biochemistry
May 14, 2024
0
48
The COVID-19 pandemic resulted in millions of deaths. Despite an unparalleled collaborative research effort that led to effective vaccines and therapies being produced in record-breaking time, a complete understanding of ...
Biochemistry
May 14, 2024
0
33
Researchers at the Paul Scherrer Institute PSI have—for the first time—precisely characterized the enzyme styrene oxide isomerase, which can be used to produce valuable chemicals and drug precursors in an environmentally ...
Biochemistry
May 14, 2024
0
25
The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics. A research team from Heinrich Heine University Düsseldorf (HHU) and Jülich Research Center (Forschungszentrum ...
Biochemistry
May 13, 2024
0
21
A team led by Prof Frank Glorius from the Institute of Organic Chemistry at the University of Münster has developed an evolutionary algorithm that identifies the structures in a molecule that are particularly relevant for ...
Biochemistry
May 10, 2024
0
86
Sometimes, serendipity—or just plain luck—still plays a pivotal role in scientific discovery. Recently, a team of chemists was experimenting with using a biocatalytic process to trigger a cyclopropanation reaction, which ...
Biochemistry
May 10, 2024
0
26
Boronic acid has been used in organic chemistry for decades, even though it is not present in any organism. "It gives rise to different chemical reactions than those we find in nature," explains Gerard Roelfes, Professor ...
Biochemistry
May 8, 2024
0
453
In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. However, there are hundreds of different kinases in the ...
Biochemistry
May 8, 2024
0
130
Red blood cells (RBCs) transport oxygen throughout the body and are able to pass through a complex of narrow capillaries due to their ability to deform. "The deformability of RBCs is an important indicator of their health ...
Biochemistry
May 8, 2024
0
7