An activity-based probe library for identifying protein function

Proteins are vital to living systems. They build and repair tissues, act as enzymes to speed chemical reactions, regulate hormones and transport nutrients—all of which are important for developing next-generation bioproducts ...

'Green thumb' molecule helps leaf stalks grow in crowded conditions

Potassium (K) is one of the three essential nutrients for plants. It plays a critical role in a wide range of processes, including cell growth, photosynthesis and regulation of water balance. Plants take up K from the soil ...

How stressed cells put the brakes on protein 'shipping'

Cells synthesize proteins in the endoplasmic reticulum (ER), and these proteins are transported to the Golgi apparatus for distribution to their ultimate destinations inside and outside the cell. The structures that transport ...

Predictive tools can confuse rare mutations with dangerous ones

When a patient's DNA is read, it is compared with a reference version of the human genome. This allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs. Most variations will ...

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