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Unraveling the complexities of the Borna disease virus 1

Cases of Borna disease virus 1 (BoDV-1) are extremely rare in humans, but in those who develop disease, the outcome is severe, almost always resulting in fatal encephalitis or inflammation in the brain. This zoonotic virus ...

Alzheimer's-linked protein tau plays a role in cell division

All processes such as wound healing, hair growth, and the replacement of old cells with new ones depend on cell division. During this process, chromosomes inside the cell must be evenly divided between two daughter cells. ...

Turning uncertainty into a design tool for AI-engineered molecules

While precision seems critical for science, researchers from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Texas A&M University are embracing uncertainty, using it to fine-tune artificial intelligence ...

This giant virus just gave up its atomic blueprint

A research group has successfully determined, for the first time in the world, the capsid (outer shell) structure of Melbournevirus—a member of the giant virus family—at a resolution of 4.4 Å using cryo-electron microscopy ...

One DNA letter can trigger complete sex reversal

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. In the new study, published in Nature Communications, a single-letter insertion in a non-coding ...

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AI uncovers hidden immune defenses inside bacteria
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Climate change may speed evolution through inherited gene regulation changes
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Mathematical model predicts fish freshness in real time
Cell & Microbiology
The binding sites that guide fungal 'vesicle hitchhiking'—new study maps mRNA transport
Cell & Microbiology
Glucose transport may hinge on a fleeting transition-like state
Cell & Microbiology
This protein helps cancer cells survive treatment—and points to new treatments
Cell & Microbiology
Researchers clarify how cells remove damaged endoplasmic reticulum
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Network analysis reveals mammal food web drivers across Africa
Biotechnology
3D microscopy reveals how a tick-borne virus reshapes human cells to replicate
Biotechnology
What this AI epitope library means for vaccines, immunotherapy and biosensors
Biotechnology
Molecular 'leash' measures force-sensing protein activation at about 15 piconewtons
Molecular & Computational biology
AI is reengineering drug discovery by speeding up testing and scanning petabytes of data
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Ak4 regulates mitochondrial DNA synthesis to control macrophage antibacterial activity, research finds
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Matcha model makes drug candidate screening more than 30 times faster
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Evolution
Mutant clownfish reveals how nature draws boundaries
Cell & Microbiology
Scientists identify potential new target for disrupting mosquito reproduction
Plants & Animals
Fish 'steals' glowing protein: Genome sequencing proves unique survival strategy
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Astronomers find evidence for three subpopulations of merging black holes
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High-resolution imaging captures cavity-induced density waves in a quantum gas
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Flux pathway reveals why mussel-like liquid phase separation can happen in seconds
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A nanoscale robotic cleaner can hunt, capture and remove bacteria
Other
Saturday Citations: Octopus behavior; children's nightmares; the fast effects of meditation
Condensed Matter
'Poor man's Majoranas' can be used as quantum spin probes
Space Exploration
After Artemis II, NASA looks to SpaceX, Blue Origin for moon landings
Earth Sciences
Worsening ocean heat waves are 'supercharging' hurricane damage, study finds
General Physics
Search for dark matter intensifies as leading detector reaches milestone
Earth Sciences
Yellowstone's magma source may be closer than thought, reshaping hazard models
Earth Sciences
Glaciers rapidly declining, with extreme losses in 2025
Earth Sciences
Yellowstone's magma plumbing mainly shaped by tectonic forces—not deep mantle plume
Optics & Photonics
Scientists turn 'mess' into breakthrough: Chaotic design unlocks next-generation optical devices
Archaeology
Archaeological survey at Gnith reveals new details about pearl millet's westward expansion
Astronomy
Peculiar core-collapse supernova breaks the mold with a long, dim plateau
General Physics
Dual-frequency Paul trap shows potential for synthesizing antihydrogen outside of CERN
Earth Sciences
Back-to-back Amazon droughts trigger record forest stress
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Universal surface-growth law confirmed in two dimensions after 40 years
Space Exploration
Parachutes: A vital part of Artemis II's trip home
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SoCal's hybrid bees outsmart Varroa mites before they even hatch

Synthetic gene medicines may disrupt DNA repair

Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is shown in a new study from Karolinska Institutet, published in Nature Communications. The findings ...

Tech upgrade reveals even finer transcription detail inside cells

In 2021, a technology developed at the University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at microscopic resolution, enabling researchers to measure all expressed ...

'Plug-and-play'—how plants steal genetic shortcuts to survive

Plants are fast-tracking their own evolution by "plugging in" genetic code stolen from their neighbors, according to new research that reveals the secret to their own successful genetic engineering. The study, led by Catherine ...

High-performance cell atlas workflow driven by manifold fitting

Researchers from the National University of Singapore (NUS) have developed CellScope, a high-performance single-cell analysis framework that uses manifold fitting to analyze single-cell RNA sequencing (scRNA-seq) data. This ...

Genetic mapping of rice stink bug aids crop pest control

Even though farmers have been dealing with rice stink bugs as pests since the 1880s, entomologists are still getting to know them at the genetic level. A first-of-its-kind study published on the genetics of rice stink bugs ...

Study identifies aging-associated mitochondrial circular RNAs

New research profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human cohorts and probes how mitochondrial circRNAs and the mitochondrial RNA-binding protein GRSF1 relate ...

Integrating genomics insights with game theory

The Microbiology Society's Microbiology Outlooks, launched in 2025, has published its inaugural article: "When Theory Meets Genomics: Reconciling Game Dynamics and Within-Host Evolution." The new commentary explores how theoretical ...