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Molecular & Computational biology news
Researchers develop lysosomal 'TRAP' for clearance of viruses and variants
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a neotype lysosomal trap for clearing viruses and variants. This lysosomal "TRAP" (lysoTRAP) shows efficient ...
Biotechnology
46 minutes ago
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Researchers develop light-guided siRNA delivery system based on cyanobacteria
In a study published in Cell Reports Physical Science on Nov. 25, a research team reported the development of an innovative intelligent light-guided biohybrid system, the CTPA/siCSF1R system, to target tumor-associated macrophages ...
Biotechnology
2 hours ago
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Keeping a cell's nucleolus compact may be key to fighting aging
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were elucidated in yeast, a model ...
Cell & Microbiology
19 hours ago
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New transformer-based AI model enhances precision in rice leaf disease detection
Rice is one of the world's most essential food crops, but its production is constantly threatened by leaf diseases caused by pathogens such as fungi, bacteria, and viruses. These diseases, which manifest as spots or blotches ...
Molecular & Computational biology
19 hours ago
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Mathematical modeling reveals the explosive secret of the squirting cucumber
A team led by the University of Oxford has solved a mystery that has intrigued scientists for centuries: how does the squirting cucumber squirt?
Plants & Animals
20 hours ago
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Framework uncovers what makes large numbers of 'squishy' grains start flowing in biological processes
Researchers Samuel Poincloux (currently at Aoyama Gakuin University) and Kazumasa A. Takeuchi of the University of Tokyo have clarified the conditions under which large numbers of "squishy" grains, which can change their ...
Molecular & Computational biology
20 hours ago
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New mechanism in bacterial DNA enzyme opens pathways for antibiotic development
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present ...
Cell & Microbiology
20 hours ago
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Scientists develop AI tool for personalized phage therapy as a targeted alternative to antibiotics
With the rapid development of antibiotics in the 1930s, phage therapy—using viruses known as bacteriophages or phages to tackle bacterial infections—fell into oblivion. But as the current rise in antibiotic resistance ...
Cell & Microbiology
22 hours ago
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Cyanobacterial circadian clock uses an AM radio-like mechanism to control cellular processes
Cyanobacteria, an ancient lineage of bacteria that perform photosynthesis, have been found to regulate their genes using the same physics principle used in AM radio transmission.
Cell & Microbiology
22 hours ago
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Fuji apple study finds genetic mechanisms behind high-yield trees
Apples rank among the world's most valuable fruit crops, with production spanning more than 100 countries. Some apple trees naturally develop into what farmers call "spur-type" varieties—compact trees that are more productive ...
Molecular & Computational biology
23 hours ago
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Hidden pocket in human bitter taste receptor discovered
A new study describes an exciting discovery that changes the way we understand human bitter taste receptors. The research has revealed a hidden "pocket" inside one of the body's bitter taste receptors, called TAS2R14.
Cell & Microbiology
23 hours ago
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Research on key host pathways has implications for Ebola and beyond
Mortality rates from Ebola outbreaks can be as high as 90%, according to the Centers for Disease Control and Prevention, and 55 people died in the most recent outbreak in Uganda in 2022.
Cell & Microbiology
Nov 25, 2024
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Decoding the cellular basis of floral fragrance
Floral fragrances are nature's allure, enticing pollinators and helping plants adapt to environmental challenges. These scents, primarily generated in petals, consist of complex compounds such as terpenoids and benzenoids/phenylpropanoids, ...
Plants & Animals
Nov 25, 2024
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Molecular morphers: DNA-powered gels shape-shift on command
Johns Hopkins engineers have developed gel strips that change shape when given chemical instructions written in DNA code. These "gel automata," measuring just centimeters, can grow or shrink, transforming from one letter ...
Biotechnology
Nov 25, 2024
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New tools filter noise from evolution data
While rates of evolution have appeared to accelerate over short time periods, new analysis suggests that statistical noise is affecting the data patterns. A professor at the University of Tennessee, Knoxville, and his colleague ...
Evolution
Nov 24, 2024
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'e-Drive': New gene drive reverses insecticide resistance in pests... then disappears
Insecticides have been used for centuries to counteract widespread pest damage to valuable food crops. Eventually, over time, beetles, moths, flies and other insects develop genetic mutations that render the insecticide chemicals ...
Molecular & Computational biology
Nov 22, 2024
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Gene regulation study reports surprising results: Extensive regions of DNA belong to multiple gene switches
Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are therefore separated ...
Evolution
Nov 22, 2024
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tRNAs help some mRNAs get lost in translation
Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized and translated into more protein, while directing others to be degraded and limiting how much protein ...
Molecular & Computational biology
Nov 22, 2024
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New technique points to unexpected uses for snoRNA across many cell types
Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence cellular processes, disease development, and overall organismal health. Small nucleolar RNAs (snoRNAs) ...
Cell & Microbiology
Nov 22, 2024
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AI and genus-conditioned algorithms create precise simulation-ready models of 600,000 existing urban trees
The Irish philosopher George Berkely, best known for his theory of immaterialism, once famously mused, "If a tree falls in a forest and no one is around to hear it, does it make a sound?" What about AI-generated trees? They ...
Ecology
Nov 22, 2024
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