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A scaffold at the center of our cellular skeleton

All animal cells have an organelle called a centrosome, which is essential to the organization of their cell skeleton. The centrosome plays fundamental roles, especially during cell division, where it allows equal sharing ...

How to keep the nucleus clean

Cells are small factories that constantly produce protein and RNA molecules by decoding the genetic information stored in the DNA of their chromosomes. The first phase of this decoding, the transcription process, 'transcribes' ...

Artificial intelligence yields new antibiotic

Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory tests, the drug killed many of the world's most problematic disease-causing bacteria, including some strains ...

Curing genetic disease in human cells

While the genome editing tool CRISPR/Cas9, developed in 2012, cuts a mutation out of a gene and replaces it with a gene-piece, a newer type of CRISPR, called base-editing, can repair a mutation without cutting the DNA. Therefore, ...

Fungal pathogens tap human iron stores to survive immunity

Candida species, the most prevalent opportunistic human fungal pathogens, affect severely immunocompromized individuals, and can cause severe invasive infections. The steep increase in infections by multidrug-resistant Candida ...

Chlamydia's covert reproduction

UF researchers have resolved a two-decade old mystery centered upon how the bacteria chlamydia divide and reproduce. Newly published results from the lab of Anthony Maurelli, a microbiologist in UF's College of Public Health ...

New class of enzymes could lead to bespoke diets, therapeutics

Everyone seems to have an opinion about which foods to eat or avoid, how to lose weight (and keep it off!), and which superfood to horde. But there's a better place to search for health secrets than in a tropical berry: the ...

Unexpected insights into the dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes. ...

Researchers discover how cells clear misfolded proteins from tissues

Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings. The study, which will be published February 18 in the Journal of ...

Atomic structures mapped in measles, mumps, flu and RSV

Northwestern University researchers have, for the first time, determined the 3-D atomic structure of a key complex in paramyxoviruses, a family of viruses that includes measles, mumps, human parainfluenza and respiratory ...

Reproductive genome from the laboratory

The field of synthetic biology does not only observe and describe processes of life but also mimics them. A key characteristic of life is the ability for replication, which means the maintenance of a chemical system. Scientists ...

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Molecular & Computational biology
De novo genes far more common and important than scientists thought
Bioengineers developing organisms without biological parents
New CRISPR-based tool can probe and control several genetic circuits at once
Physically producing computer-generated artificial genomes to understand DNA
Transparent human organs allow 3-D maps at the cellular level
Cell & Microbiology
Biologists investigate the role of the largest animal brain cells
Cell & Microbiology
Leaking away essential resources actually helps cells grow
Cell & Microbiology
Computer simulations visualize how DNA is recognized to convert cells into stem cells
Molecular & Computational biology
Tiny, erratic protein motor movements revealed
Molecular & Computational biology
Mechanism of controlling autophagy by liquid-liquid phase separation revealed
Cell & Microbiology
Cryo-electron microscopy opens a door to fight Epstein-Barr
Plants & Animals
How a tiny and strange marine animal produces unlimited eggs and sperm over its lifetime
Molecular & Computational biology
Mathematical model reveals behavior of cellular enzymes
Molecular & Computational biology
How cellular machinery labels proteins for degradation
Cell & Microbiology
Neuron-like activity detected in an unforeseen place
Cell & Microbiology
Alternatives to antibiotics found in sheep poo and on human skin
Cell & Microbiology
Autophagy degrades liquid droplets—but not aggregates—of proteins
Cell & Microbiology
Huge bacteria-eating viruses close gap between life and non-life
Control of a mitochondrial protective mechanism identified
Technology takes a step forward in genetic research

Other news

How newborn stars prepare for the birth of planets
Sub-Neptune sized planet validated with the habitable-zone planet finder
Earth Sciences
Huge stores of Arctic sea ice likely contributed to past climate cooling
Study finds microbes can alter an environment dramatically before dying out
Bio & Medicine
Researchers show what drives a novel, ordered assembly of alternating peptides
Analytical Chemistry
Pill-sized 'heater' could increase accessibility in diagnosing infectious disease
DNA from ancient packrat nests helps unpack Earth's past
Social Sciences
Study of African society inspires broad thinking about human paternity, fidelity
General Physics
Physicists grab individual atoms in groundbreaking experiment
Microchannel network hydrogel-induced ischemic blood perfusion connection
To help students think in 3-D, a geologist turns to paper model making
Soft Matter
How are microbes attracted to an oil spill?
Plants & Animals
Cyanobacteria problems will worsen if carbon concentrations continue to rise
Earth Sciences
The Earth formed much faster than previously thought
Quantum Physics
ALPHA collaboration reports first measurements of certain quantum effects in antimatter
Cell & Microbiology
Research team tackles superbug infections with novel therapy
Plants & Animals
Social networks reveal dating in blue tits
Eighteen-hour-year planet on edge of destruction
Plants & Animals
More clues for how the monkeyflower got its spots
Plants & Animals
First genetic evidence of resistance in some bats to white-nose syndrome, a devastating fungal disease