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The future of malaria control is … more mosquitoes?

South Africa's malaria elimination teams could soon have backup from millions of decoy mosquitoes specially bred at Africa's first mosquito factory. These insects are part of South Africa's pioneering Sterile Insect Technique ...

Pumping antibiotics out: A new route to bacterial drug resistance

Bacteria can survive antibiotics in several ways, including by pumping the drugs out of their cells before they can take effect. Researchers at the University of Osaka have discovered a previously unknown mechanism that allows ...

Changing the antibiotic playbook to catch an ESKAPE artist

Nearly a century ago, a single colony of Staphylococcus aureus (S. aureus) helped launch the antibiotic age. In 1928, Alexander Fleming returned to his London lab to find that a stray mold had wiped out the Staphylococcus ...

An activity-based probe library for identifying protein function

Proteins are vital to living systems. They build and repair tissues, act as enzymes to speed chemical reactions, regulate hormones and transport nutrients—all of which are important for developing next-generation bioproducts ...

Predictive tools can confuse rare mutations with dangerous ones

When a patient's DNA is read, it is compared with a reference version of the human genome. This allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs. Most variations will ...

'Green thumb' molecule helps leaf stalks grow in crowded conditions

Potassium (K) is one of the three essential nutrients for plants. It plays a critical role in a wide range of processes, including cell growth, photosynthesis and regulation of water balance. Plants take up K from the soil ...

A molecular brake that keeps muscle architecture in check

Every movement we make, from blinking to sprinting, depends on the ability of muscle fibers to contract in a rapid and coordinated way. Achieving this precision requires an intricate internal membrane network known as the ...

How stressed cells put the brakes on protein 'shipping'

Cells synthesize proteins in the endoplasmic reticulum (ER), and these proteins are transported to the Golgi apparatus for distribution to their ultimate destinations inside and outside the cell. The structures that transport ...

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Cell & Microbiology
Completing the connectome: How pursuing a map of the fly brain rewired neuroscience
Plants & Animals
Tiny crustacean helps scientists understand genes regulating circatidal rhythms
Evolution
When biology inspires mathematics: Hidden symmetries explain why widely used evolutionary methods can give false answers
Biotechnology
Eight-letter DNA alphabet is accurately transcribed by a natural enzyme
Biotechnology
Mammalian genes can combine to make previously unknown mRNAs and proteins
Cell & Microbiology
Cellular maintenance crew may miss as much as half of certain misfolded proteins
Cell & Microbiology
A new layer of the human genome: Embedded RNA marks may reshape DNA twisting
Cell & Microbiology
How cells teach themselves to move together
Cell & Microbiology
New model explains how bacterial promoter elements set gene activity and regulation
Cell & Microbiology
Researchers identify the world's first cell line with the KMT2A::SEPTIN6 fusion gene
Evolution
In tune with nature: Human speech follows a rhythm that is also found in the animal kingdom
Cell & Microbiology
Hidden protein recycling hubs discovered inside human sperm cells
Biotechnology
AI-informed AdaptiveFlow redefines large-scale cloud computing for drug discovery
Cell & Microbiology
Diatom sequencing project finds striking genetic differences among microscopic algae
Biotechnology
New AI model maps the ion binding sites that control how proteins work
Cell & Microbiology
Growing bacteria line up single-file, then buckle in liquid crystals
Molecular & Computational biology
Magnetic beads streamline large-scale analysis of disease-linked glycopeptides
Cell & Microbiology
Algorithm improves detection of differentially expressed genes in large single-cell trajectory data sets
Molecular & Computational biology
New AI approaches to help understand complex biological data
Molecular & Computational biology
Anti-influenza therapies that target the host

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Astronomy
Extremely massive galaxy proto-supercluster smashes distance record
Archaeology
Did wildfires help spark the invention of pottery?
Earth Sciences
Sparse-data method estimates sea surface temperatures 40% more accurately than conventional approach
Analytical Chemistry
A crystalline sponge reveals structures of large 'beyond rule of 5' molecules
Earth Sciences
Cosmic radiation at flight altitudes rises when the sun is less active
Earth Sciences
Physics-based AI unlocks first global predictions of carbon cycling in ocean sediments
Earth Sciences
Plants' response to rising CO₂ could put the brakes on dryland expansion
Archaeology
Waterlogged seeds reveal melons' ancient journey
Nanomaterials
Curved nanographene with five-, six- and seven-membered rings synthesized in two steps
Astronomy
Fast radio bursts could help disentangle galactic feedback from dark matter effects
Astrobiology
Giant impacts may strip small icy moons of subsurface oceans
Optics & Photonics
Helium-3 lifts new quantum computing concept with faster tunneling rates
Archaeology
Beyond the sea walls: Underwater archaeology reveals the hidden scale of ancient Mediterranean ports
Space Exploration
Martian air could yield methane rocket fuel with fewer unwanted byproducts
Quantum Physics
A new game demonstrates quantum advantage with provable classical limits
General Physics
A photon that challenges Einstein: According to current physics, it should never have reached Earth
Nanophysics
New molecular magnet design boosts performance for ultrahigh-density data storage
Plants & Animals
Star-fingered toads use fingertip lobules to detect prey in murky water
Earth Sciences
New iron-bearing compounds could store water near Earth's core
Astronomy
Hubble and Webb find that far-out solar system objects 'remember' the past