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Molecular & Computational biology news
AI and biophysical modeling unite for novel protein design
An interdisciplinary research team from Leipzig University and the Saxon AI center ScaDS.AI has developed a novel approach that integrates artificial intelligence (AI) methods with biophysical modeling. This innovative strategy ...
Molecular & Computational biology
Feb 14, 2025
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From liquid to solid: New technique uncovers disease-related changes in tiny droplets within our cells
Understanding the behavior of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a method to study how these droplets transition from liquid to solid. This change ...
Cell & Microbiology
Feb 14, 2025
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CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.
Biotechnology
Feb 14, 2025
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Water molecules help proteins read the human genome, research reveals
In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, have discovered that water molecules play a crucial role in ...
Molecular & Computational biology
Feb 14, 2025
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Feet first: Understanding how mRNA helps cells 'walk'
Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different cells are shuttled around. ...
Cell & Microbiology
Feb 14, 2025
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Celebrating World Pangolin Day with new genomes to aid the world's most trafficked animal
Pangolins are unique as they are the only mammal to be covered in scales. Even though they are scaly, photos of them are typically met with "awwws" from the viewers, who find them adorable. Importantly, though, pangolins ...
Plants & Animals
Feb 14, 2025
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Genetic study of Greenlanders reveals variants specific to their culture
An international team of geneticists, public health specialists and environmental scientists from Greenland, Denmark and several other countries in Europe has conducted a genetic analysis of Greenlanders to learn more about ...
Developmental biologists discover how a critical protein shapes gallbladder formation
The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt University, has demonstrated that the formation of the gallbladder and bile duct system depends ...
Molecular & Computational biology
Feb 13, 2025
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Fungus 'hacks' natural immune system to cause neurodegeneration in fruit flies
A fungal infection has been shown to trigger a fruit fly's own immune system to destroy brain cells, leading to signs of neurodegeneration, a new study has found.
Plants & Animals
Feb 13, 2025
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Deep learning provides new view on 300 million years of brain evolution
In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define brain cell types across species. They trained deep learning models on human, mouse, and chicken brain ...
Evolution
Feb 13, 2025
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Mutation in rice alters sterility temperature, offering new agricultural insights
Thermo-sensitive genic male sterility 5 (tms5) is a widely used thermo-sensitive genic male sterile (TGMS) line for two-line hybrid rice production. Critical sterility-inducing temperature (CSIT) acts as a key threshold of ...
Molecular & Computational biology
Feb 13, 2025
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Gene editing approach sheds light on how mitochondria drive autophagy
Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning proteins and organelles. By reusing these basic molecules, the cell gains the energy and resources needed ...
Cell & Microbiology
Feb 13, 2025
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The evolution of evolution itself: How evolution got so good at evolving
The field of evolution examines how organisms adapt to their environments over generations, but what about the evolution of evolution itself?
Evolution
Feb 13, 2025
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World's largest digital microbe collection aims to transform health research
Researchers at University of Galway have created the world's largest collection of digital microbes—nearly a quarter million computer models—to help revolutionize our understanding of the human microbiome and its impact ...
Cell & Microbiology
Feb 13, 2025
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Researchers unlock new potential porcine virus treatment
UConn researchers have identified a novel small molecule for the development of a preventative treatment for a serious and costly disease in pigs.
Molecular & Computational biology
Feb 13, 2025
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Bacterial flagellar motors: Study sheds light on their ion-driven mechanisms
When speaking of motors, most people think of those powering vehicles and human machinery. However, biological motors have existed for millions of years in microorganisms. Among these, many bacterial species have tail-like ...
Cell & Microbiology
Feb 13, 2025
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'ChatGPT for birdsong' may shed light on how language is wired in the human brain
Just like ChatGPT and other generative language models train on human texts to create grammatically correct sentences, a new modeling method by researchers at Penn State trains on recordings of birds to create accurate birdsongs. ...
Plants & Animals
Feb 12, 2025
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The minor spliceosome: Researchers reveal new structural insights into an essential RNA-protein complex
In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell select this information? A large molecular machine called the spliceosome continuously separates the ...
Cell & Microbiology
Feb 12, 2025
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Some viruses 'freeze' their RNA to replicate, study finds
They say that change takes time. Well, that's not the case for RNA. The small biological molecule acts like a switchboard operator, capable of changing its shape every few milliseconds so it can manipulate biological functions ...
Cell & Microbiology
Feb 12, 2025
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Unraveling the complex role of climate in dengue dynamics
Researchers have unveiled new insights into how weather influences the spread of dengue fever. Their study identifies temperature and rainfall as critical factors driving the global surge in dengue cases and offers actionable ...
Ecology
Feb 12, 2025
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Data-driven techniques enhance understanding of cell division
How a breeding network could build a genetic pathway to more productive and climate-smart livestock in Africa
Researchers achieve highest-quality moss genome assembly to date
Gut bacteria can alter brain proteins: New glycosylation method uncovers link
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'Work flow' music designed to improve performance does just that
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Advanced computational tool reveals cellular development processes
Minecraft players can now explore whole cells and their contents
Scientists produce first complete genome of a banana slug
