Unraveling structure and function relationships in synthetic cell receptors
Northwestern University researchers have identified structural features in engineered cell receptors that correlate with variations in receptor function.
Biotechnology news
NanoCas, a smaller version of CRISPR tested with a single AAV, delivers on-target results
Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform gene editing in non-liver tissues, including skeletal muscle, using a single adeno-associated virus ...
Scientists develop self-sustained protein transport and tissue assembly in artificial cells
In a new Nature Communications study, scientists have developed a novel method for artificial cells to interact with their external environment without the need for complex modification processes.
Something to sniff at: Lab-engineered receptors illuminate odor detection
A team of researchers led by Duke University, the University of California San Francisco, and the Beckman Research Institute of the City of Hope have engineered odorant receptors to reveal the molecular basis of odor discrimination.
New high-speed video system uses sensors, infrared illumination to track insects in large wild areas
Our ability to learn more about insect behavior—which affects ecology, health, and economy on a global scale—depends largely on suitable recording technology. But until now, these tools have been considerably limited.
A DNA assembly kit to unlock the CRISPR-Cas9 potential for metabolic engineering
The clustered regularly interspaced short palindrome repeats (CRISPR) and Crispr-associated protein 9 (CRISPR/Cas9) is now a well-known, revolutionary method to engineer microbial cells.
Fish-on-Chips: An optofluidic platform to investigate the neural and chemosensory axes of zebrafish
Neuroscientists study chemosensory processing by establishing chemical cues and the corresponding behavioral responses to record large-scale neuronal activity. In a new report now published in Nature Communications, Samuel ...
Engineering circular ribonucleic acids (circRNAs) for improved protein production
Circular ribonucleic acids (circRNAs) are a promising platform for gene expression studies as a stable and prevalent ribonucleic acid in eukaryotic cells, which arise from back-splicing. In a new report now published in Nature ...
Study evaluates deep learning models that decode the functional properties of proteins
Deep learning–based language models, such as BERT, T5, XLNet and GPT, are promising for analyzing speech and texts. In recent years, however, they have also been applied in the fields of biomedicine and biotechnology to ...
Interfacing gene circuits with microelectronics through engineered population dynamics
The ability to detect the growth of a bacterial colony by monitoring changes in impedance (a measure of resistance) across time reflects the impressive scientific progress connecting bacterial behavior with electrodes via ...
