Mapping a route to stem cell therapies
Monash University researchers are shedding light on the complex processes that underpin the creation and differentiation of stem cells, bringing closer the promise of 'miracle' therapies.
Monash University researchers are shedding light on the complex processes that underpin the creation and differentiation of stem cells, bringing closer the promise of 'miracle' therapies.
Cell & Microbiology
May 20, 2013
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Tuberculosis-causing mycobacteria use a select group of proteins known as virulence factors to transmit the disease, which infects roughly one third of the world's population and causes 1.7 million deaths annually. Those ...
Cell & Microbiology
Nov 27, 2017
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Even in a calm, unchanging environment, cells are not static. Among other actions, cells activate and then deactivate some types of transcription factors—proteins that control the expression of genes—in a series of unpredictable ...
Cell & Microbiology
Oct 21, 2015
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While great strides have been achieved in cancer treatment, scientists are looking for the new targets and next generation of therapeutics to stop this second leading cause of death nationwide. A new platform for drug discovery ...
Biochemistry
Sep 9, 2013
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Gene expression can be turned on and off like a switch, or it can be finely adjusted , as with a volume control knob. Dr Garth Ilsley, research scientist in Prof. Nick Luscombe's unit at the Okinawa Institute of Science and ...
Biotechnology
Feb 8, 2016
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Life is almost unbearably complex. Humans and mice, frogs and flies toggle genes on and off in dizzying combinations and sequences during their relentless march from embryo to death. Now scientists seeking to understand the ...
Biotechnology
May 2, 2010
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(Phys.org) —Gaining control of the ability of mature tissues to generate stem cells is the central medical challenge of our day. From taming cancer, to providing compatible cell banks for replacement organs, knowledge of ...
In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...
Biotechnology
Jul 1, 2013
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When our organs age or wear out, their renewal usually depends on a few stem cells in the tissue, because the vast majority of differentiated cells have lost their ability to divide and generate new cells. A German-French ...
Cell & Microbiology
Jan 21, 2016
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Human embryonic stem cells (hESCs) retain the ability to form any cell type in the body. They do this thanks to the interplay of many proteins, including one involved in cell signaling known as extracellular signal-regulated ...
Cell & Microbiology
Sep 25, 2013
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