'DNA microscopy' offers entirely new way to image cells
Microscopy just got reinvented—again.
Microscopy just got reinvented—again.
Cell & Microbiology
Jun 20, 2019
4
12
Analysis of the first fully-sequenced genome of the Siberian hamster shows how these small, seasonal breeders adapt their bodies and energy usage to survive the winter.
Biotechnology
Jun 10, 2019
0
96
Researchers have been using "Fluorescence in situ hybridization" (FISH) analysis for decades to literally fish for specific DNA and RNA sequences in intact cells and tissues within their vast seas of nucleic acid molecules. ...
Biotechnology
May 20, 2019
0
60
A Massachusetts General Hospital (MGH) research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, ...
Biotechnology
Apr 17, 2019
0
189
Biomedical engineers at Duke University have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. They believe it can be easily translated to any of the editing technology's ...
Biotechnology
Apr 15, 2019
1
372
Scientists have improved their understanding of a new form of cell-cell communication that is based on extracellular RNA (exRNA). RNA, a molecule that was thought to only exist inside cells, now is known to also exist outside ...
Cell & Microbiology
Apr 4, 2019
1
400
Scientists for the first time have found strong evidence that RNA and DNA could have arisen from the same set of precursor molecules even before life evolved on Earth about four billion years ago.
Biochemistry
Apr 1, 2019
59
906
Much like our fight-or-flight response, our cells also have a stress autopilot mode. An oxygen dropoff, overheating, or an invading toxin can trigger the cellular stress response – a cascade of molecular changes that are ...
Cell & Microbiology
Jan 24, 2019
0
77
Messenger RNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases. The biggest obstacle to this approach so far has been finding safe and efficient ways to deliver ...
Materials Science
Jan 4, 2019
2
775
Our prehistoric Earth, bombarded with asteroids and lightning, rife with bubbling geothermal pools, may not seem hospitable today. But somewhere in the chemical chaos of our early planet, life did form. How? For decades, ...
Biochemistry
Dec 3, 2018
7
495