Two mutations in the melanocortin 2 receptor gene—which is involved in the production of the stress hormone cortisol—may have played a role in the domestication of dogs by allowing them to develop social cognitive skills ...
Evolution
Jun 9, 2022
0
64
Your cells need to get around. For example, immune cells must roam around your body to locate sites of infection, and neurons must migrate to specific positions in the brain during development. But cells do not have eyes ...
Cell & Microbiology
Jun 9, 2022
0
174
Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
0
5
Scientists from the Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne, Germany, have discovered a novel biochemical mechanism explaining how immune proteins defend plants against invading ...
Cell & Microbiology
May 20, 2022
0
70
The bark of the Galbulimima belgraveana tree, found only in remote rainforests of Papua New Guinea and northern Australia, has long been used by indigenous people for both healing and ceremony. A tea brewed from the bark ...
Biochemistry
May 13, 2022
1
218
The human body consists of trillions of cells that constantly communicate with one another. A central role in this communication process is played by receptor proteins on the cell surface. Since they often serve as drug targets, ...
Cell & Microbiology
May 6, 2022
0
24
A new study from North Carolina State University examines immune system diversity in the critically endangered Wyoming toad and finds that genetic bottlenecks could impact a species' ability to respond to new pathogens. The ...
Plants & Animals
Apr 28, 2022
0
2
A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...
Cell & Microbiology
Apr 21, 2022
0
8
G protein-coupled receptors (GPCRs) play a crucial role in cell signal transduction and comprise the largest drug target protein family. Despite recent breakthroughs in structural and pharmacological studies of these receptors, ...
Cell & Microbiology
Apr 20, 2022
0
65
Cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1) is a critical enzyme involved in gonadal steroidogenesis, including androgen and estrogen production. Among sex steroids, androgen signaling disruption is known ...
Plants & Animals
Apr 15, 2022
0
3
