Related topics: receptors · cancer cells · cells

Tracing water channels in cell surface receptors

G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...

Treating pain by blocking the 'chili-pepper receptor'

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...

New technology offers insight into cholesterol

With new advanced techniques developed by the Copenhagen Center for Glycomics at the University of Copenhagen it is possible to study cells in greater detail than ever before. The findings have just been published in the ...

New molecule enables quick drug monitoring

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants. However, current methods are expensive, ...

Solving a complex protein problem

Many proteins undergo processing within cellular compartments called the endoplasmic reticulum and the Golgi apparatus. Transit between these structures is facilitated by transport vesicles, which bubble out from the membranes ...

X-ray laser at SLAC maps important drug target

(Phys.org) —Researchers have used one of the brightest X-ray sources on the planet to map the 3-D structure of an important cellular gatekeeper known as a G protein-coupled receptor, or GPCR, in a more natural state than ...

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