News tagged with protein kinase
Protein associated with learning implicated in causing grasshoppers to swarm
New research has found that a protein associated with learning and memory plays an integral role in changing the behaviour of locusts from that of harmless grasshoppers into swarming pests.
Dec 19, 2011 |
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Study finds promising clue to mechanism behind gene mutation that causes Parkinson's disease
Researchers at Mount Sinai School of Medicine have discovered a way that mutations in a gene called LRRK2 may cause the most common inherited form of Parkinson's disease. The study, published online this month in the journal ...
Medicine & Health / Medical research
Mar 25, 2011 |
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New clues discovered regarding how immune cells operate
(PhysOrg.com) -- Researchers at the University of Dundee have identified control mechanisms that allow certain white blood cells, which have a vital role in fighting viral infections and dealing with organ transplants, to ...
Medicine & Health / Medical research
Mar 23, 2011 |
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New functional understanding outlines therapy for untreatable breast cancer
Cancer biologists from the Friedrich Miescher Institute for Biomedical Research have been part of a collaborative effort that identified a novel rationale for the treatment of currently not curable triple-negative ...
Mar 07, 2011 |
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PET scans may allow early prediction of response to targeted therapy of thyroid cancer
Positron emission tomography (PET) can image metabolic changes following treatment with the protein kinase inhibitor vandetanib, helping to define the therapy response or the effectiveness of the therapeutic agent, according ...
Feb 01, 2011 |
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Calcium flow disruptions linked to heart failure
Excessive release of calcium inside cardiac muscle can cause sudden cardiac death in heart failure patients. New research has revealed how this could happen, opening up new possibilities for combating heart ...
Medicine & Health / Medical research
Jan 31, 2011 |
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On...off...on...off... The circuitry of insulin-releasing cells
A myriad of inputs can indicate a body's health bombard pancreatic beta cells continuously, and these cells must consider all signals and "decide" when and how much insulin to release to maintain balance in blood sugar, for ...
Dec 09, 2010 |
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Ultraviolet light helps skin cancer cells thrive, researchers report
The sun's ultraviolet light activates an enzyme that helps skin cancer cells survive and proliferate, researchers report.
Dec 07, 2010 |
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Newly discovered regulatory mechanism essential for embryo development and may contribute to cancer
Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth. When the ...
Oct 28, 2010 |
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Drug to treat alcoholism goal of UH professor's research
With the ultimate goal to discover a drug that one day treats alcoholism, a University of Houston (UH) pharmacy professor is working on pinpointing the mechanisms in the brain that respond to alcohol.
Medicine & Health / Medical research
Sep 20, 2010 |
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New understanding of the 'flight-or-fight' response
New research in the Journal of General Physiology helps explain how the body's "flight-or-fight" response is mediated. The study, which may provide new answers to the question of how the heart pacemaker—the sinoatrial (SA) n ...
Medicine & Health / Psychology & Psychiatry
Aug 16, 2010 |
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Scientists find unsuspected molecular link between obesity and insulin resistance
A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say scientists from Dana-Farber Cancer Institute ...
Medicine & Health / Medical research
Jul 21, 2010 |
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Unlocking the secrets of cellular energy holds promise for obesity, diabetes and cancer
(PhysOrg.com) -- A breakthrough on how cells regulate their energy is promising for clinical gains into diseases such as obesity, diabetes and cancer. Researchers at McGill University and University of Pennsylvania have uncovered ...
Medicine & Health / Medical research
Jul 20, 2010 |
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Identification of a novel tumor suppressor
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI), have identified a novel tumor suppressor playing an important role in T-cell lymphoma. The protein kinase NDR1 ...
Jun 21, 2010 |
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TGen partner, PBS-Bio, makes first breakthrough drug analysis
Predictive Biomarker Sciences Inc. (PBS-Bio) has completed its first drug analysis, enabling Canadian biotech company PharmaGap Inc. to significantly advance a potentially significant anti-cancer medication.
Medicine & Health / Medications
Jun 18, 2010 |
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Protein kinase
A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.
For more information about Protein kinase, read the full article at
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