Proteins are the workhorses of life, mediating almost all biological events in every life form. Scientists know how proteins are structured, but folding - how they are built - still holds many mysteries.
Biochemistry
Mar 31, 2016
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14
A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety ...
Biochemistry
Jan 7, 2011
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0
A graduate student's surprise observation in fundamental experiments with small binding molecules at work in protein folding has allowed biochemists at the University of Massachusetts Amherst to develop the first firm mathematical ...
Biochemistry
Mar 15, 2017
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114
On October 26th Nature will publish a study that overturns the decades-old textbook model of action for a protein that is central for many processes in living cells. Researchers at the FOM Institute AMOLF and the University ...
Cell & Microbiology
Oct 26, 2016
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20
A protein's folding patterns help them perform their dedicated tasks. As the real "doers" of the cell, even a tiny alteration in a protein's amino acid backbone can cause misfolding and hinder the protein's functionality ...
Biochemistry
Sep 4, 2018
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19
Cellular proteins are produced as long chains of amino acids that must fold precisely into their final shape. The key players in this folding process are the so-called molecular chaperones, protein helpers that make sure ...
Biochemistry
Apr 26, 2018
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23
An international team of researchers have discovered a new type of transition in protein folding: amyloid crystals formed from amyloid fibrils by a decrease in energy. The crystals are even more stable than the fibrils, which ...
Biochemistry
Nov 7, 2017
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12
(Phys.org)—Acidity (pH) and its changes play an important role in many physiological processes, including protein folding, and can act as indicators of cancer. In the journal Angewandte Chemie, American researchers have ...
Nanomaterials
Dec 14, 2012
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When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope—a sort of cellular traffic camera—University of Illinois chemists now can watch the way ...
Cell & Microbiology
Dec 9, 2014
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0
You are taking a class on origami and Mr. Otaki asks you to fold that little red piece of paper into a very elaborate design. You have to do it in a very short time. You try your best but you fail. Your origami sucks!
Biochemistry
May 11, 2015
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23
