A new study of both computer-created and natural proteins suggests that the number of unique pockets – sites where small molecule pharmaceutical compounds can bind to proteins – is surprisingly small, meaning drug side ...
Biochemistry
May 20, 2013
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(Phys.org)—Cornell researchers have discovered that a protein known for moving cells around in the body also helps regulate a cellular organelle responsible for generating one-third of all proteins in the human body.
Cell & Microbiology
Dec 21, 2012
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John Crocker had expected to see a flat line—a familiar horizontal track with some slight peaks and valleys—but the plot of energy in front of him dove sharply downward.
Analytical Chemistry
Dec 5, 2022
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(Phys.org) —In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could ...
Nanophysics
Jun 27, 2013
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Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With ...
Molecular & Computational biology
Aug 1, 2023
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235
Biophysicists at the Technische Universitaet Muenchen (TUM), Germany, have published the results of single-molecule experiments that bring a higher-resolution tool to the study of protein folding. How proteins arrive at the ...
General Physics
Jan 19, 2010
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Musicians are helping scientists analyze data, teach protein folding and make new discoveries through sound.
Other
Feb 17, 2022
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Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein ...
Molecular & Computational biology
Jan 19, 2022
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A new method to induce protein folding by taking the pressure off of proteins is up to 100 times faster than previous methods, and could help guide more accurate computer simulations for how complex proteins fold, according ...
Biochemistry
Jun 1, 2009
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(Phys.org) -- A new method for looking at how proteins fold inside mammal cells could one day lead to better flu vaccines, among other practical applications, say Cornell researchers.
Biochemistry
Jul 26, 2012
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