Chromosome-folding theory shows promise
Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.
Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.
Cell & Microbiology
Apr 28, 2015
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In proper society of yesterday, the chaperone insured that couples maintained proper courting rituals. In biology, a group of proteins called chaperonins makes sure that proteins are folded properly to carry out their assigned ...
Cell & Microbiology
Jan 20, 2010
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José Onuchic has become an expert at connecting the dots, but finding connections merely implied by the dots well, that's quite a trick.
Biochemistry
Jun 12, 2012
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In silico prediction of protein folding has the potential to reveal the specificity of a given protein sequence for DNA. Such methods are particularly promising as they could open the road to the rational design of novel ...
Cell & Microbiology
Oct 15, 2012
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Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.
Cell & Microbiology
Aug 27, 2019
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Researchers have discovered a second giant pore for the transport of folded proteins in certain cell organelles, i.e. peroxisomes. Five years ago, the group already described the first giant pore. The team headed by Prof ...
Cell & Microbiology
Dec 4, 2015
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Biophysicists at JILA have measured protein folding in more detail than ever before, revealing behavior that is surprisingly more complex than previously known. The results suggest that, until now, much about protein behavior ...
Biochemistry
Mar 2, 2017
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Proteins are the workhorses of the cell and thus responsible for almost all biological functions including metabolism, signal transmission or the determination of the cell's shape. However, before they can fulfill their various ...
Cell & Microbiology
May 9, 2014
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A study developed by researchers at the Faculty of Physics of the University of Barcelona (UB), published in the journal Physical Review Letters, describes the contribution of water to the three-dimensional structure of proteins ...
Condensed Matter
Sep 21, 2015
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To make paper, manufacturers must break down cellulose (chunks of wood pulp), a process that currently requires large amounts of energy and toxic chemicals like chlorine. Nature performs the same task using enzymes, non-toxic ...
Materials Science
Jan 30, 2014
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