News tagged with pore complex

Researchers construct a device that mimics one of nature's key transport machines

(PhysOrg.com) -- To help protect its genes, a cell is highly selective about what it allows to move in and out of its nucleus. Yet that choosiness is regulated by just a thin barrier, perforated with tiny ...

Biology /

created Jan 06, 2009 | popularity 4.7 / 5 (7) | comments 0

Biologists reveal structure of cell nucleus 'gatekeeper'

(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.

Biology / Cell & Microbiology

created Oct 27, 2009 | popularity 4.2 / 5 (6) | comments 6

The breakdown of barriers in old cells may hold clues to aging process

Like guards controlling access to a gated community, nuclear pore complexes are communication channels that regulate the passage of proteins and RNA to and from a cell's nucleus. Recent studies by researchers ...

Biology /

created Jan 22, 2009 | popularity 5 / 5 (4) | comments 0

'Cell surgery' using nano-beams

Using a simple glass capillary, atomic physicists at RIKEN are developing an ultra-narrow ion beam that pinpoints a part of organelles in a living cell, enabling biologists to visualize how the damage affects ...

Physics / General Physics

created Apr 04, 2011 | popularity 4 / 5 (4) | comments 0

Structural study backs new model for the nuclear pore complex

(PhysOrg.com) -- In higher organisms, the genetic material is confined and protected in the cell nucleus. In order for a healthy cell to function, the DNA must send manufacturing orders through the double ...

Biology /

created Dec 24, 2008 | popularity 4.7 / 5 (3) | comments 0

New fluorescence technique opens window to protein complexes in living cells

Fluorescent microscopy makes use of molecules, such as green fluorescent protein (GFP), that emit colored light when illuminated with light of a specific wavelength. Molecules like GFP can be used to label proteins of interest ...

Chemistry / Biochemistry

created Sep 21, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research suggests core nuclear pore elements shared by all eukaryotes

(PhysOrg.com) -- For perhaps 1.8 billion years after life first emerged on Earth, a sort of evolutionary writer’s block stalled the development of organisms more complicated than single cells. Then, a burst of experimental ...

Chemistry / Biochemistry

created Jul 13, 2009 | popularity 5 / 5 (1) | comments 0

'Promiscuous' protein interactions found in the nuclear pore complex

(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...

Biology / Cell & Microbiology

created Sep 29, 2009 | popularity 5 / 5 (1) | comments 0

Quantum dots track who gets into cell nucleus

(PhysOrg.com) -- UC Berkeley researchers Karsten Weis, Jan Liphardt, and colleagues have used fluorescent probes called quantum dots to determine which molecules get into the nucleus via its nano-pores and ...

Nanotechnology / Bio & Medicine

created Sep 02, 2010 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Trigger mechanism provides 'quality control' in cell division

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division ...

Biology / Cell & Microbiology

created Nov 22, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Polarized microscopy technique shows new details of how proteins are arranged

Whether you're talking about genes, or neurons, or the workings of a virus, at the most fundamental level, biology is a matter of proteins. So understanding what protein complexes look like and how they operate is the key ...

Chemistry / Analytical Chemistry

created Apr 17, 2011 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Research reveals novel transport mechanism for large ribonucleoproteins

The movement of genetic materials, such as RNA and ribosomes, from the nucleus to the cytoplasm is a critical component in a cell's ability to make the proteins necessary for essential biological functions. Until now, it ...

Biology / Cell & Microbiology

created May 10, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast