In mammals, females have a limited supply of oocytes. Oocytes have a unique epigenome with approximately half the DNA methylation of sperm, and the most terminally differentiated somatic cells. Until recently, regulators ...
Biotechnology
Nov 29, 2018
0
55
The promise of generating truly pluripotent stem cells from terminally differentiated adult cell types continues to captivate scientists who envision great potential for therapeutic interventions. The two primary methods ...
Cell & Microbiology
Jul 3, 2018
0
4
A longstanding obstacle to the market for bovine embryos is lipid accumulation in oocytes. Researchers have now described a hitherto unknown mechanism of lipid accumulation in oocytes that limits the success of in vitro production ...
Other
Aug 22, 2017
0
1
Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
0
4
Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional building blocks required to support a growing embryo. ...
Cell & Microbiology
Jan 28, 2016
0
20
The protein necessary for fertility in both sexes performs distinctly different roles in male and female gametes, according to a groundbreaking study, which included researchers from the University of Georgia College of Veterinary ...
Cell & Microbiology
Jan 30, 2015
0
70
Muhammad Anzar, a research scientist for Agriculture and Agri-Food Canada, is an expert in cryopreservation—you know, freezing living matter to cheat death.
Biochemistry
Jan 19, 2015
0
30
Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save millions ...
Cell & Microbiology
Jul 17, 2014
0
0
Over the last few decades, scientists have drawn upon a powerful arsenal of biotechnology techniques to establish a wide variety of genetically engineered mouse strains. These animals represent invaluable resources for studying ...
Biotechnology
Aug 16, 2013
3
0
From obesity to substance abuse, from anxiety to cancer, genetically modified mice are used extensively in research as models of human disease. Researchers often spend years developing a strain of mouse with the exact genetic ...
Biotechnology
Jun 26, 2013
1
0
