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Researchers discover drug resistance mechanisms in most common form of melanoma

Researchers with UCLA's Jonsson Comprehensive Cancer Center have found that melanoma patients whose cancers are caused by mutation of the BRAF gene become resistant to a promising targeted treatment through another genetic ...

Medicine & Health / Cancer

created Nov 24, 2010 | popularity 5 / 5 (3) | comments 1 | with audio podcast

Using cancer's weapons against it

(PhysOrg.com) -- Tumours seem to pacify our immune system by tapping into our bodies’ codes, but we may be able to use this trick against them in our bid to hunt them down.

Medicine & Health / Medical research

created Oct 08, 2010 | popularity 4.8 / 5 (13) | comments 5 | with audio podcast

Melanoma-initiating cell identified

Scientists at the Stanford University School of Medicine have identified a cancer-initiating cell in human melanomas. The finding is significant because the existence of such a cell in the aggressive skin cancer has been ...

Medicine & Health / Cancer

created Jun 30, 2010 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Lung cancer and melanoma laid bare: First comprehensive analysis of two cancer genomes

Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes. All cancers are caused by mutations in the DNA of cancer cells which are acquired during a person's lifetime. ...

Medicine & Health / Cancer

created Dec 16, 2009 | popularity 5 / 5 (4) | comments 0

Study: Cancer may pass from mother to unborn child

(PhysOrg.com) -- A new study has provided genetic evidence for the first time that it is possible for a mother to transmit cancer to her unborn child via the placenta.

Medicine & Health / Cancer

created Oct 14, 2009 | popularity 5 / 5 (2) | comments 0 weblog

Glowing Cornell dots -- a potential cancer diagnostic tool set for human trials

The U.S. Food and Drug Administration (FDA) has approved the first clinical trial in humans of a new technology: Cornell Dots, brightly glowing nanoparticles that can light up cancer cells in PET-optical imaging.

Nanotechnology / Bio & Medicine

created Jun 13, 2011 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Studies find new drugs boost skin cancer survival

(AP) -- They're not cures, but two novel drugs produced unprecedented gains in survival in separate studies of people with melanoma, the deadliest form of skin cancer, doctors reported Sunday.

Medicine & Health / Cancer

created Jun 06, 2011 | popularity not rated yet | comments 0

FDA clears first melanoma drug to extend life

(AP) -- The Food and Drug Administration has approved a breakthrough cancer medication from Bristol-Myers Squibb Co. that researchers have heralded as the first drug to prolong the lives of patients with ...

Medicine & Health / Medications

created Mar 25, 2011 | popularity 4.3 / 5 (4) | comments 1

Arthritis drug could help beat melanoma skin cancer

A breakthrough discovery by the University of East Anglia (UEA) and Children's Hospital Boston promises an effective new treatment for one of the deadliest forms of cancer.

Medicine & Health / Cancer

created Mar 23, 2011 | popularity 4.8 / 5 (4) | comments 5 | with audio podcast

Novel method could improve the performance of proteins used therapeutically

Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when administered therapeutically. The technique should be useful to increase potency, slow ...

Medicine & Health / Medical research

created Mar 09, 2011 | popularity not rated yet | comments 0 | with audio podcast

Researchers predict age of T cells to improve cancer treatment

Manipulation of cells by a new microfluidic device may help clinicians improve a promising cancer therapy that harnesses the body's own immune cells to fight such diseases as metastatic melanoma, non-Hodgkin's ...

Biology / Biotechnology

created Mar 02, 2011 | popularity not rated yet | comments 0 | with audio podcast

Nanosponges harvest rare cancer marker from blood

Cancer researchers have long hypothesized that tumors release small amounts of proteins that could serve as earlier diagnostic indicators of cancer, but the search for such biomarkers has been hampered by the presence of ...

Nanotechnology / Bio & Medicine

created Jan 19, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Researchers make major breakthrough in melanoma research

In a breakthrough that could lead to new treatments for patients with malignant melanoma, researchers from Mount Sinai School of Medicine have discovered that a particular protein suppresses the progression of melanoma through ...

Medicine & Health / Cancer

created Dec 22, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

New approaches refine molecular imaging for detecting cancer metastasis

(PhysOrg.com) -- Researchers may be a step closer to improving the detection of metastatic tumors in an organism - in real time - using a non-invasive approach that pairs an imaging agent with a genetic element that only ...

Medicine & Health / Cancer

created Dec 16, 2010 | popularity not rated yet | comments 0 | with audio podcast

Killing drug-resistant melanoma requires combination therapy

This past summer saw a revolution in melanoma therapy. Patients whose melanoma lesions contain a mutation in the BRAF gene were successfully treated with a BRAF-specific inhibitor, PLX4032. Reports of the ...

Medicine & Health / Cancer

created Dec 13, 2010 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Melanoma

Melanoma (pronounced /ˌmɛləˈnoʊmə/ ( listen)) is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the less common types of skin cancer but causes the majority of skin cancer related deaths. Malignant melanoma is a serious type of skin cancer. It is due to uncontrolled growth of pigment cells, called melanocytes. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a Breslow thickness greater than 1 mm.

Around 160,000 new cases of melanoma are diagnosed nationally each year, and it is more frequent in males and Caucasians. It is more common in Caucasian populations living in sunny climates than in other groups. According to a WHO report about 48,000 melanoma related deaths occur worldwide per year.

Malignant melanoma accounts for 75 percent of all deaths associated with skin cancer.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy.

For more information about Melanoma, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: skin cancer , cancer , cancer cells , cells , tumor cells