PC deficiency suppresses seipin: New insights into Berardinelli-Seip congenital lipodystrophy type 2
Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), the most severe form of lipodystrophy that leads to loss of nearly all subcutaneous fat tissue, is caused by mutations in the BSCL2/seipin gene. Seipin is an integral ...