News tagged with hematopoietic stem cells
Researchers parse the origins of hematopoietic stem cells
Researchers at the University of California, San Diego School of Medicine have identified a gene and a novel signaling pathway, both critical for making the first hematopoietic stem cells (HSCs) in developing ...
Jun 08, 2011 |
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Researchers develop platform to monitor hematopoietic stem cells
A Canadian research team has developed an automated microfluidic cell culture platform to monitor the growth, survival and responses of hundreds of hematopoietic stem cells (HSCs) at the single cell level.
May 22, 2011 |
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Prostate cancer spreads to bones by overtaking the home of blood stem cells
Like bad neighbors who decide to go wreck another community, prostate and breast cancer usually recur in the bone, according to a new University of Michigan study.
Mar 23, 2011 |
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How long do stem cells live?
When patients receive a bone marrow transplant, they are getting a new population of hematopoietic stem cells. Fresh stem cells are needed when a patient is low on red blood cells, as in anemia, or white blood cells, which ...
Medicine & Health / Medical research
Mar 01, 2011 |
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Unappreciated dynamism of blood cell production
The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in the Journal of Experimental Medicine.
Medicine & Health / Medical research
Feb 07, 2011 |
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Stem cell discovery could lead to improved bone marrow transplants
Researchers at the University of California, Santa Cruz, have identified a key molecule for establishing blood stem cells in their niche within the bone marrow. The findings, reported in the January issue of Cell Stem Ce ...
Jan 06, 2011 |
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Poor breast cancer prognosis associated with presence of circulating tumor, cancer stem cells
Metastatic breast cancer patients whose blood contains circulating tumor cells (CTCs) before or after treatment with high-dose chemotherapy and blood stem cell transplant have shorter survival periods, according to a new ...
Dec 10, 2010 |
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Adipose tissue produces cells involved in immune response
French researchers from CNRS and the Universite Paul Sabatier have demonstrated the existence, in adipose tissue, of stem cells similar to those found in bone marrow. These cells are capable of differentiating into mast cells, ...
Nov 26, 2010 |
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Gene therapy for metastatic melanoma in mice produces complete remission
A potent anti-tumor gene introduced into mice with metastatic melanoma has resulted in permanent immune reconfiguration and produced a complete remission of their cancer, according to an article to be published in the December ...
Nov 18, 2010 |
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RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors
Therapeutic lentiviral vectors are emerging as vital tools for molecular medicine as evidenced by the growing number of clinical trials using these vector systems. From a basic research standpoint, lentiviral vectors are ...
Medicine & Health / Medical research
Sep 30, 2010 |
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Inhibiting cell signaling pathway may improve bone marrow transplant success rate
Identification of a molecular communications pathway that influences the mobilization of hematopoietic (blood) stem cells could lead to targeted therapies for improving bone marrow transplant success rates.
Medicine & Health / Medical research
Sep 26, 2010 |
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Researchers identify how bone-marrow stem cells hold their 'breath' in low-oxygen environments
UT Southwestern Medical Center researchers have identified unique metabolic properties that allow a specific type of stem cell in the body to survive and replicate in low-oxygen environments.
Medicine & Health / Medical research
Sep 03, 2010 |
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Scientist discovers stem cell 'partnership' that could advance regenerative medicine
A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. ...
Medicine & Health / Medical research
Aug 17, 2010 |
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MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
Investigators have identified a new mechanism that controls the number of hematopoietic stem cells - cells that give rise to all blood and immune system cells. In a report in the online Early Edition of Proceedings of th ...
Medicine & Health / Medical research
Aug 04, 2010 |
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Biologists discover microRNAs that control function of blood stem cells
Hematopoietic stem cells provide the body with a constant supply of blood cells, including the red blood cells that deliver oxygen and the white blood cells that make up the immune system. Hematopoietic -- or blood -- stem ...
Aug 04, 2010 |
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Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are multipotent stem cells that give rise to all the blood cell types including myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has undergone considerable revision in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. Recently, long-term transplantation experiments point toward a clonal diversity model of hematopoietic stem cells. Here, the HSC compartment consists of a fixed number of different types of HSC, each with epigenetically preprogrammed behavior. This contradicts older models of HSC behavior, which postulated a single type of HSC that can be continuously molded into different subtypes of HSCs. HSCs constitute 1:10.000 of cells in myeloid tissue.
For more information about Hematopoietic stem cell, read the full article at
Wikipedia.
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