Structural studies offer 'how-to' guide for designing cancer drugs
To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.
To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.
Biochemistry
Dec 9, 2022
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82
Everyone knows someone who has had cancer. In 2020, around 19 million new cases—and around 10 million deaths—were registered worldwide. Treatments are improving all the time, but can damage healthy cells or have severe ...
Biochemistry
Dec 7, 2022
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438
EPFL researchers have discovered that it is not just molecular density, but also pattern and structural rigidity, that control super-selective binding interactions between nanomaterials and protein surfaces. The breakthrough ...
Biochemistry
Nov 22, 2022
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37
For cancer cells to grow and spread around the human body, they need proteins that bind copper ions. New research about how cancer-related proteins bind the metal and how they interact with other proteins, opens up potential ...
Biochemistry
Nov 10, 2022
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360
Physicists at McMaster University have identified a natural delivery system which can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria by using red blood cells as a vehicle.
Cell & Microbiology
Oct 31, 2022
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53
A new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College ...
Cell & Microbiology
Oct 25, 2022
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48
University of Central Florida material sciences engineers Melanie Coathup and Sudipta Seal have designed a cerium oxide nanoparticle—an artificial enzyme—that protects bones against damage from radiation. The nanoparticle ...
Bio & Medicine
Sep 26, 2022
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154
Nanoparticles can be used as powerful vehicles to administer vaccines and prevent serious illness, as with the treatment of COVID-19 and to deliver chemotherapeutic drugs to cancer cells with goal of eradicating the cancer ...
Bio & Medicine
Sep 20, 2022
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6
A cell dies of ferroptosis when free radicals get out of control and destroy the protective cell membrane in a chain reaction. Healthy cells are occasionally affected when they come under oxidative stress. But cancer cells ...
Biochemistry
Sep 19, 2022
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101
A new method of separating cancer cells from non-cancer cells has been developed by researchers at the Wellcome Sanger Institute, in a boost for those working to better understand cancer biology using single-cell mRNA sequencing.
Cell & Microbiology
Sep 7, 2022
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23