Cell on a chip reveals protein behavior
A simplified version of an artificial cell produces functional proteins and even sorts them.
Mar 18, 2013
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Mar 18, 2013
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The complexity of regulated development in plants
In most living organisms, growth and development are controlled by selective modification of the lifespans of particular proteins. This mechanism is especially prevalent in plants, allowing rapid moderation ...
Mar 15, 2013
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Timing germ cell development
(Phys.org) —Scientists from the Friedrich Miescher Institute for Biomedical Research identify a novel mechanism in early germ cell development. They show how the chromatin modulator PRC1 coordinates the ...
Mar 15, 2013
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Researchers develop new sensor for methylated DNA
Collaborators from Mayo-Illinois Alliance for Technology Based Healthcare have developed a new, single molecule test for detecting methylated DNA. Methylation—the addition of a methyl group of molecules to a DNA strand—is ...
Mar 14, 2013
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Important find shows how gene regulators select different partners to form different organs
Scientists at the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) have discovered that key gene regulators work in pairs to trigger stem cells to differentiate into specific cell ...
Mar 14, 2013
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Protein abundant in cancerous cells causes DNA 'supercoiling'
A team of USC scientists has identified a protein that can change DNA topology, making DNA twist up into a so-called "supercoil."
Mar 11, 2013
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Practicing medicine at the nanoscale: New approaches to drug delivery offer hope for new, more targeted treatments
Modern medicine is largely based on treating patients with "small-molecule" drugs, which include pain relievers like aspirin and antibiotics such as penicillin.
Mar 11, 2013
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Disease knowledge may advance faster with CRISPR gene probing tool
Scientists at UC San Francisco have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs ...
Mar 07, 2013
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Dual systems key to keeping chromosomes intact
USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable – while it is being unzipped for replication.
Mar 07, 2013
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Epigenetics unveils how plants may adapt to environments throughout the world
Scientists at the Salk Institute for Biological Studies have identified patterns of epigenomic diversity that not only allow plants to adapt to various environments, but could also benefit crop production ...
Mar 06, 2013
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New chemical probe provides tool to investigate role of malignant brain tumor domains
In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Profes ...
Mar 01, 2013
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DNA's twisted communication: Genome organization key element for control of gene expression
During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in ...
Feb 28, 2013
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Flipping the 'off' switch on cell growth
A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery ...
Feb 22, 2013
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Life's tiniest architects pinpointed
If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, Yale School of Medicine researchers report Feb. 21 in the journal Developmental Ce ...
Feb 21, 2013
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Understanding termite digestion could help biofuels, insect control
A termite's own biology with help from microorganisms called protists, are keys to the insect's digestion of woody material, according to a Purdue University scientist.
Feb 19, 2013
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