An article titled "m6A RNA modification as a new player in R-loop regulation," by the Dynamic Gene Regulation research group led by Arne Klungland at IMB, was published in the January edition of Nature Genetics.
Biotechnology
Jan 29, 2020
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Studies of human populations and animal models suggest that a father's experiences such as diet or environmental stress can influence the health and development of his descendants. How these effects are transmitted across ...
Cell & Microbiology
Oct 17, 2018
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Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic 'memory' ...
Cell & Microbiology
Oct 12, 2016
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Research from Oxford University published today in the journal Genome Research has found that a special combination of epigenetic modifications crucial to stem cell growth evolved in animals much earlier than previously appreciated. ...
Biotechnology
Sep 13, 2018
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Fish farming can make food supplies more stable while itself becoming more sustainable, according to researchers in Hungary and Norway.
Molecular & Computational biology
Mar 6, 2023
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In Florida carpenter ant colonies, distinct worker castes called minors and majors exhibit pronounced differences in social behavior throughout their lives. In a new study published today in Science, a multi-institution team ...
Cell & Microbiology
Dec 31, 2015
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(Medical Xpress)—Individual body odour plays an important role in partner selection. Humans, mice, fish and birds, and probably other vertebrates too, receive important information about a potential partner's immune system ...
Biotechnology
Feb 1, 2013
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Paul Kammerer committed suicide in 1926 after being accused of fraud in his famous experiments of "inheritance of acquired traits" with the midwife toad. A new study shows how recent advances in molecular epigenetics and ...
Evolution
Oct 31, 2016
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Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development. The once radical idea that such changes in gene expression can be ...
Cell & Microbiology
Sep 26, 2022
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374
A growing body of evidence suggests that environmental stresses can cause changes in gene expression that are transmitted from parents to their offspring, making "epigenetics" a hot topic. Epigenetic modifications do not ...
Biotechnology
Sep 18, 2014
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In biology, and specifically genetics, epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence – hence the name epi- (Greek: επί- over, above, outer) -genetics. Examples of such changes might be DNA methylation or histone deacetylation, both of which serve to suppress gene expression without altering the sequence of the silenced genes. In 2011, it was demonstrated that the methylation of mRNA has a critical role in human energy homeostasis. This opened the field of RNA epigenetics.
These changes may remain through cell divisions for the remainder of the cell's life and may also last for multiple generations. However, there is no change in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism's genes to behave (or "express themselves") differently.
One example of epigenetic changes in eukaryotic biology is the process of cellular differentiation. During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo which in turn become fully differentiated cells. In other words, a single fertilized egg cell – the zygote – changes into the many cell types including neurons, muscle cells, epithelium, endothelium of blood vessels etc. as it continues to divide. It does so by activating some genes while inhibiting others.
This text uses material from Wikipedia, licensed under CC BY-SA
