Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs. The study, published in the scientific journal Nature Chemistry, proposes a new way of facing the discovery ...
Biochemistry
Dec 2, 2016
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5
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure. In spite of the ...
Biochemistry
Aug 16, 2016
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9
Scientists have described an improved, cost-efficient method to isolate membrane proteins, a class of proteins that are the targets of more than 60 percent of approved therapeutic drugs.
Cell & Microbiology
Jul 25, 2016
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5
Nanoparticles are being studied as drug delivery systems to treat a wide variety of diseases. New research delves into the physical properties of nanoparticles that are important for successfully delivering therapeutics within ...
Bio & Medicine
Jul 18, 2016
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4
Using DESY's ultra bright X-ray source PETRA III, scientists have resolved the molecular structure of two promising drug candidates from the new group of Spiegelmers for the first time. The results provide a deeper understanding ...
Biochemistry
Apr 22, 2015
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17
By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically—an approach that could help identify novel targets for therapies against ...
Cell & Microbiology
Apr 3, 2015
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817
Acne, a scourge of adolescence, may be about to meet its ultra high-tech match. By using a combination of ultrasound, gold-covered particles and lasers, researchers from UC Santa Barbara and the private medical device company ...
Bio & Medicine
Mar 19, 2015
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143
Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery—it is extremely ...
Biotechnology
Nov 17, 2014
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0
A new effort mapping 24-hr patterns of expression for thousands of genes in 12 different mouse organs – five years in the making – provides important clues about how the role of timing may influence the way drugs work ...
Biotechnology
Oct 27, 2014
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0
Ludwig Maximilian University of Munich researchers report that a new class of chemical compounds makes cancer cells more sensitive to chemotherapeutic drugs. They have also pinpointed the relevant target enzyme, thus identifying ...
Biochemistry
Sep 30, 2014
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