Research examines how to optimize nanoparticles for efficient drug delivery

July 18, 2016, Wiley

Nanoparticles are being studied as drug delivery systems to treat a wide variety of diseases. New research delves into the physical properties of nanoparticles that are important for successfully delivering therapeutics within the body, with a primary focus on size. This is especially important as relatively subtle differences in size can affect cell uptake and determine the fate of nanoparticles once within cells.

By exploring various strategies for fabricating nanoparticles, the investigators provide valuable information for generating uniform in high yields that will be efficiently taken up by target cells.

The research appears in the first issue of Bioengineering & Translational Medicine, which is also a special issue entitled "Nanoparticles in Medicine: targeting, optimization and clinical applications."

Explore further: Glass now has smart potential

More information: Sahar Rahmani et al, Engineering of Nanoparticle Size via Electrohydrodynamic Jetting, Bioengineering & Translational Medicine (2016). DOI: 10.1002/btm2.10010

Related Stories

Glass now has smart potential

June 7, 2016

Australian researchers at the University of Adelaide have developed a method for embedding light-emitting nanoparticles into glass without losing any of their unique properties – a major step towards 'smart glass' applications ...

Researchers hack the metastatic process using nanoparticles

July 6, 2016

Memorial Sloan Kettering Cancer Center (MSK) molecular pharmacologist Daniel Heller, PhD, and colleagues have identified a new strategy to target drugs specifically to cancer sites, including metastatic tumors. The approach ...

Drug delivery that hits the dot

May 24, 2016

Drug treatments are made more efficient by delivering them to specific sites in the body where they are needed. For example, specific targeting of anticancer drugs to tumour sites could reduce required doses, provide more ...

New 'uikidama' nanoparticle structure revealed

June 13, 2016

Sometimes it is the tiny things in the world that can make an incredible difference. One of these things is the nanoparticle. Nanoparticles may be small, but they have a variety of important applications in areas such as, ...

Recommended for you

Engineers produce smallest 3-D transistor yet

December 10, 2018

Researchers from MIT and the University of Colorado have fabricated a 3-D transistor that's less than half the size of today's smallest commercial models. To do so, they developed a novel microfabrication technique that modifies ...

New traffic rules in 'Graphene City'

December 6, 2018

In the drive to find new ways to extend electronics beyond the use of silicon, physicists are experimenting with other properties of electrons, beyond charge. In work published today (Dec 7) in the journal Science, a team ...

Artificial synapses made from nanowires

December 6, 2018

Scientists from Jülich together with colleagues from Aachen and Turin have produced a memristive element made from nanowires that functions in much the same way as a biological nerve cell. The component is able to save and ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.