Related topics: cancer cells · chromosomes · dna damage

How bacteria control their cell cycle

Researchers at the Biozentrum of the University of Basel have demonstrated how bacteria coordinate cell division with the replication of their genetic material. In an interdisciplinary study they explain why the current concept ...

Coordinating the removal of RNA-DNA hybrids

Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. ...

Completing DNA synthesis

The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial ...

Scientists unwind mystery behind DNA replication

The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...

A catalog of DNA replication proteins

Maintenance of genome integrity—and prevention of diseases such as cancer—requires complete and faithful replication of the genome every cell division cycle.

Chromosome structure inspires intricate works of art

A collaboration between a Virginia Tech entomology professor, art professor, and computer science professor working in biophysics has resulted in the creation of stunning works of art that can help researchers and the public ...

DNA replication machinery captured at atom-level detail

July 15, 2019) Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. St. Jude Children's Research Hospital scientists have determined at atomic resolution the ...

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