Ribose-seq identifies and locates ribonucleotides in genomic DNA
Ribonucleotides, units of RNA, can become embedded in genomic DNA during processes such as DNA replication and repair, affecting the stability of the genome by contributing to DNA fragility and mutability. ...
Study suggests expanding the genetic alphabet may be easier than previously thought
A new study led by scientists at The Scripps Research Institute suggests that the replication process for DNAthe genetic instructions for living organisms that is composed of four bases (C, G, A and T)is more ...
Researchers demonstrate possible primitive mechanism of chemical info self-replication
(Phys.org) -- When scientists think about the replication of information in chemistry, they usually have in mind something akin to what happens in living organisms when DNA gets copied: a double-stranded molecule ...
A $1000 genome could be reached by 2013
Scientists find a key to maintaining our DNA
DNA contains all of the genetic instructions that make us who we are, and maintaining the integrity of our DNA over the course of a lifetime is a critical, yet complex part of the aging process. In an important, albeit early ...
Enzyme corrects more than one million faults in DNA replication
Scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh have discovered an enzyme that corrects the most common mistake in mammalian DNA.
How a molecular Superman protects the genome from damage
How many times have we seen Superman swoop down from the heavens and rescue a would-be victim from a rapidly oncoming train?
Tracking DNA helps scientists trace origins of genetic errors
Scientists have shed light on how naturally occurring mutations can be introduced into our DNA.
Life, but not as we know it
A rudimentary form of life that is found in some of the harshest environments on earth is able to sidestep normal replication processes and reproduce by the back door, researchers at The University of Nottingham ...
Genesis of the enzyme that divides the DNA double helix during cell replication
The proteins that drive DNA replication—the force behind cellular growth and reproduction—are some of the most complex machines on Earth. The multistep replication process involves hundreds of atomic-scale ...
Marching to our own sequence: Study finds DNA replication timing varies among people
Imagine being asked to copy a library of books. Doing it yourself would take forever. You'd probably call some friends and come up with a plan to divide and conquer.
Crucial step in human DNA replication observed for the first time
(Phys.org) —For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan ...
Bacteria are hard-wired for survival, E. coli study suggests
Some bacteria are able to thrive even when under continued attack, scientists have found, in a development that may help explain how our immune systems can't always prevent infections.
Flipping the 'off' switch on cell growth
A protein known for turning on genes to help cells survive low-oxygen conditions also slows down the copying of new DNA strands, thus shutting down the growth of new cells, Johns Hopkins researchers report. Their discovery ...