M6P deficiency leaves B cells out of sorts

A group of white blood cells known as B cells, which play a key role in the human immune response, need a protein-targeting signal called mannose 6-phosphate (M6P) in order to proliferate, differentiate, and present immune ...

'Stealth' nanoparticles could improve cancer vaccines

Cancer vaccines have recently emerged as a promising approach for killing tumor cells before they spread. But so far, most clinical candidates haven't worked that well. Now, scientists have developed a new way to deliver ...

Mechanism of dengue virus entry into cells revealed

Dengue fever, an infectious tropical disease caused by a mosquito-borne virus, afflicts millions of people each year, causing fever, headache, muscle and joint pains and a characteristic skin rash. In some people the disease ...

Synthetic polymer could stop the spread of HIV

A precisely designed macromolecule that mimics the binding of HIV to immune system cells could be used to stop the virus from physically entering the body, according to a new study led by a materials scientist at Queen Mary ...

Boosting immune therapy for cancer with nanoparticles

(Phys.org) —Activating the body's immune system to attack cancer and prevent it from recurring is one of the Holy Grails of cancer research because of its ability to specifically target cancer and to search almost anywhere ...

Researchers strike gold with nanotech vaccine

Scientists in the US have developed a novel vaccination method that uses tiny gold particles to mimic a virus and carry specific proteins to the body's specialist immune cells.

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