News tagged with cisplatin
Why cancer drugs lose their power: Platinum-based cancer drugs destroy tumor cells by binding to DNA strands
(PhysOrg.com) -- For 30 years, the chemotherapy drug cisplatin has been one of doctors' first lines of defense against tumors, especially those of the lung, ovary and testes. While cisplatin is often effective ...
Apr 14, 2010 |
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Nanoparticles deliver one-two therapeutic punch to kill tumor cells
The standard approach to cancer therapy today is to mix and match chemotherapy drugs in order to attack tumors in multiple ways. Now, two separate teams of investigators have demonstrated that using nanoparticles to deliver ...
Nanotechnology / Bio & Medicine
Dec 17, 2010 |
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Platinum and light together fight cancer
(PhysOrg.com) -- Researchers continue to search for cancer treatments that effectively destroy tumor cells while protecting surrounding healthy tissue and the body. One intriguing approach involves photoactivated ...
Sep 14, 2010 |
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Israel's scientists think big with the very, very small
A material just one atom thick that is stronger than steel but flexes like rubber. A "mini-submarine" that can trick the immune system and deliver a payload of chemotherapy deep inside a tumour.
Nanotechnology / Nanomaterials
Nov 09, 2010 |
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Breakthrough: With a chaperone, copper breaks through
(PhysOrg.com) -- Information on proteins is critical for understanding how cells function in health and disease. But while regular proteins are easy to extract and study, it is far more difficult to gather ...
Oct 18, 2010 |
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A more direct delivery of cancer drugs to tumors
(PhysOrg.com) -- An interdisciplinary team of researchers at Brigham and Women’s Hospital (BWH) and the Harvard-MIT Division of Health Sciences and Technology (HST) has demonstrated a better way to deliver ...
Nanotechnology / Bio & Medicine
Apr 21, 2009 |
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Inhaled nanoparticles deliver potent anticancer cocktail to lung tumors and block resistance
(PhysOrg.com) -- An ideal treatment for lung cancer would be one that could be inhaled deep into lung tissue where it would deliver tumor-killing agents that would then largely stay in the lungs, avoiding the toxicities that ...
Nanotechnology / Bio & Medicine
Nov 21, 2011 |
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Addition of trastuzumab to chemotherapy for stomach cancer extends survival by nearly 3 months
An Article published Online First by The Lancet says that for patients with HER2-positive advanced gastric cancer, addition of tastuzumab to standard cisplatinum/fluoropyrimidine chemotherapy results in a median survival of 13. ...
Aug 19, 2010 |
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'Copper pump's' potential benefit in cancer treatment
(Phys.org) -- A team of University of California, San Diego researchers has made new discoveries about a copper-transporting protein in the membranes of human cells that drug-discovery scientists can co-opt ...
May 17, 2012 |
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Elucidating side effects of antineoplastic agent
Cisplatin, an anticancer drug widely used for treating various types of tumor, can induce side effects in the short term. A team of French scientists, mostly from CNRS and the Universite de Nice has provided first in vitro ...
Oct 06, 2010 |
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Nanoparticles deliver combination chemotherapy directly to prostate cancer cells
In recent years, studies have shown that for many types of cancer, combination drug therapy is more effective than single drugs. However, it is usually difficult to get the right amount of each drug to the tumor. Now, researchers ...
Nanotechnology / Bio & Medicine
Oct 27, 2010 |
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Cancer drug cisplatin found to bind like glue in cellular RNA
An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...
Nov 21, 2011 |
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Gold used as safe driver of cancer drug
(PhysOrg.com) -- Gold nanoparticles can be used as delivery vehicles for platinum anticancer drugs, improving targeting and uptake into cells, according to research published in this month's edition of the ...
Nanotechnology / Bio & Medicine
Mar 21, 2012 |
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3-drug chemotherapy combination increases organ preservation in patients with larynx cancer
Patients with larynx cancer who received a three-drug combination of docetaxel, cisplatin and 5-fluorouracil (TPF) during induction chemotherapy were more likely to retain larynx function than were patients treated with cisplatin ...
Mar 24, 2009 |
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Researchers find new chemotherapy combination shows promise in endometrial cancer
Researchers from The University of Texas M. D. Anderson Cancer Center report that in a small study of women with advanced or recurrent endometrial cancer, gemcitabine and cisplatin, when used in combination, produced a response ...
Mar 17, 2010 |
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Cisplatin
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II) (CDDP) (trade names Platinol and Platinol-AQ) is a chemotherapy drug. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors. It was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
For more information about Cisplatin, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
