Breakthrough: With a chaperone, copper breaks through

(PhysOrg.com) -- Information on proteins is critical for understanding how cells function in health and disease. But while regular proteins are easy to extract and study, it is far more difficult to gather information about ...

Platinum and light together fight cancer

(PhysOrg.com) -- Researchers continue to search for cancer treatments that effectively destroy tumor cells while protecting surrounding healthy tissue and the body. One intriguing approach involves photoactivated drugs: an ...

'Copper pump's' potential benefit in cancer treatment

(Phys.org) -- A team of University of California, San Diego researchers has made new discoveries about a copper-transporting protein in the membranes of human cells that drug-discovery scientists can co-opt for the development ...

Cancer drug cisplatin found to bind like glue in cellular RNA

An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...

Imaging metals within cells: Identifying the proteins that bind

(Phys.org)—Metals such as copper, zinc, and iron are important nutrients to all life. The special properties of these elements that make them so useful in technologies including batteries and catalysts – for example, ...

Fine tuning an old-school chemotherapy drug

First approved by the FDA in the 1970s, the chemotherapy drug cisplatin and its relative carboplatin remain mainstays of treatment for lung, head and neck, testicular and ovarian cancer. However, cisplatin's use is limited ...

Researchers clock DNA's recovery time after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

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