Researchers at The Wistar Institute have uncovered new aspects of the three-dimensional organization of the genome, specifically how the genetic material is compacted and de-compacted in a timely fashion during the different ...
Cell & Microbiology
Oct 9, 2017
0
499
According to textbooks, proteins work by folding into stable 3D shapes that, like Lego blocks, precisely fit with other biomolecules.
Cell & Microbiology
Oct 2, 2023
0
136
Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study suggests that this steady-state ...
Cell & Microbiology
Jun 3, 2022
1
195
A single cell contains the genetic instructions for an entire organism. This genomic information is managed and processed by the complex machinery of chromatin—a mix of DNA and protein within chromosomes whose function ...
Cell & Microbiology
Jan 10, 2020
0
243
An international team of biologists has discovered how specialized enzymes remodel the extremely condensed genetic material in the nucleus of cells in order to control which genes can be used. The discovery will be published ...
Biotechnology
Jan 29, 2016
1
1085
Studying the microbiology of any entity, be it a molecule or a dolphin, ideally means putting a spotlight as close to the source material as possible. That can be especially challenging when you're investigating the Rube ...
Biochemistry
Apr 5, 2023
0
84
A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus—a finding ...
Cell & Microbiology
Sep 2, 2022
0
163
In a study published online in Nature Cell Biology on May 11, scientists from Guangzhou Institute of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences established a novel and efficient system for non-integrated ...
Cell & Microbiology
May 14, 2020
0
41
The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...
Molecular & Computational biology
Oct 17, 2019
0
76
RNA-mediated chromatin regulation is central to gene expression in many organisms but until now the mechanism of how RNA regulates chromatin packaging of DNA, and thereby switches genes on and off, has remained poorly understood.
Plants & Animals
Jun 19, 2020
0
383
