The genetic material of our cells—DNA—exists in a high-order structure called chromatin. Chromatin consists of DNA wrapped around histone proteins and efficiently packs DNA into a small volume. Moreover, using a spool ...
Molecular & Computational biology
Jan 23, 2020
0
19
Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their ...
Cell & Microbiology
Dec 3, 2019
0
116
The division of cells is a highly-regulated and complex process which requires the organised collaboration of a multitude of different cellular components. Although the basic principles are known, many components and their ...
Plants & Animals
Oct 21, 2019
0
3
Buried deep within the dazzlingly intricate machinery of the human cell could lie a key to treating a range of deadly cancers, according to a team of scientists at Florida State University.
Cell & Microbiology
Feb 26, 2019
0
96
X-ray and electron microscopy techniques help unfold the story of protein chaperones.
Biochemistry
Feb 25, 2019
0
16
An Aussie eucalypt can 'remember' past exposure to extreme heat, which makes the tree and its offspring better able to cope with future heatwaves, according to new research from Macquarie University.
Plants & Animals
Feb 14, 2019
0
18
Proteins are the workhorses of our cells, carrying out essential tasks to keep our cells – and our bodies – functioning properly. But proteins can only do their jobs if they fold into the right shape.
Cell & Microbiology
Nov 28, 2018
1
13
Researchers at the University of Freiburg report a mechanism inside cells that transports proteins to the mitochondria. Their research has now been published in the science journal Cell Reports.
Cell & Microbiology
Nov 26, 2018
0
4
For decades, molecular biologists studying a class of molecular chaperones known as heat shock proteins (Hsp70s) have relied on the Hsp70s found in bacteria as the model system. Now one of the world's experts on the molecule ...
Biochemistry
Nov 9, 2018
0
54
Small heat-shock proteins (sHSPs) are molecular chaperones that bind to unfolded proteins to prevent protein aggregation and defend against cellular stress. Mutations in human sHSPs are associated with inherited diseases ...
Biochemistry
Oct 17, 2018
0
6
