There are many processes that take place in cells that are essential for life. Two of these, transcription and translation, allow the genetic information stored in DNA to be deciphered into the proteins that form all living ...
Cell & Microbiology
Apr 13, 2017
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38
Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited simultaneously using CRISPR ...
Biotechnology
Jan 19, 2017
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8
Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now ...
Cell & Microbiology
Aug 30, 2016
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13
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
A team of researchers led by the University of Leicester has shed new light on how the regulation machinery that controls gene expression works by characterising a complex known as the NuRD complex.
Biotechnology
Apr 26, 2016
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9
What if we could program living cells to do what we would like them to do in the body? Having such control—a major goal of synthetic biology—could allow for the development of cell-based therapies that might one day replace ...
Biotechnology
Mar 14, 2016
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50
Frog embryos do not fully control which genes they can turn on or off in the beginning of their development – but their mother does, through specific proteins in the egg cell. Molecular developmental biologists at Radboud ...
Cell & Microbiology
Dec 18, 2015
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19
There are about 20,000 genes in the human genome, but not all are used in all cells at all times. At any given moment, a cell is converting only roughly half its genes into proteins. And of those active genes, about 75 percent ...
Cell & Microbiology
Dec 10, 2015
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12
Cells dynamically respond to environmental signals by turning appropriate sets of genes on or off. The "control system" that determines which genes need to be expressed at what time depends primarily on the interactions between ...
General Physics
Dec 4, 2015
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11
By tracking the movement of proteins in a living cell with nanometer-scale precision, Cornell researchers have gained a new insight into the way cells regulate the expression of their genes.
Cell & Microbiology
Jul 2, 2015
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