(Phys.org) —Two of the most exciting areas of science and technology, synthetic biology and genetic engineering, have just taken a step towards a brave new future in which large-scale synthetic biological circuits composed ...
A massive effort to map the precise binding locations of over 400 different kinds of proteins on the yeast genome has produced the most thorough and high-resolution map of chromosome architecture and gene regulation to date. ...
Biotechnology
Mar 10, 2021
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141
A high-sugar diet reprograms the taste cells in fruit flies, dulling their sensitivity to sugar and leaving a "molecular memory" on their tongues, according to a University of Michigan study.
Plants & Animals
Nov 11, 2020
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351
Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...
Cell & Microbiology
Nov 19, 2018
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70
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Biochemistry
Apr 16, 2012
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0
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure ...
Cell & Microbiology
Apr 26, 2024
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65
Researchers from Carnegie Mellon University's School of Computer Science have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing ...
Cell & Microbiology
Apr 9, 2024
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140
Single-celled organisms, such as bacteria and archaea, have developed many ways to communicate with each other. For example, they might use tiny so-called extracellular vesicles (EVs)—membrane-enveloped packages smaller ...
Cell & Microbiology
Feb 27, 2024
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7
During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.
Molecular & Computational biology
Feb 26, 2024
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14
Klebsiella pneumoniae is one of the most common and most dangerous bacterial pathogens impacting humans, causing infections of the gastrointestinal tract, pneumonia, wound infections, and even blood poisoning.
Cell & Microbiology
Feb 20, 2024
0
23
