A new "app" for finding and mapping chromosomal loci using multicolored versions of CRISPR/Cas9, one of the hottest tools in biomedical research today, has been developed by scientists at the University of Massachusetts Medical ...
Cell & Microbiology
Mar 12, 2015
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(Phys.org) —Two of the most exciting areas of science and technology, synthetic biology and genetic engineering, have just taken a step towards a brave new future in which large-scale synthetic biological circuits composed ...
Japanese researchers have developed a new, targeted method for perforating cell membranes in order to deliver drugs to, or manipulate the genes of, individual cells. The paper is published in the journal Science and Technology ...
Nanophysics
Aug 18, 2014
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(Phys.org) —In higher animals, an embryo's protein production immediately after fertilization relies on messenger RNAs (mRNAs) inherited from the mother. But shortly thereafter, the tiny organism undergoes a profound shift ...
Cell & Microbiology
Jan 30, 2014
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Static models of gene regulation networks are inevitably oversimplified, indicating how one gene specifically switches certain target genes on while turning others off. However, the reality is much more dynamic and thus noisier. ...
Biotechnology
Jan 10, 2014
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Margaret Buckingham, a Scottish-born biologist, has been awarded one of France's top science prizes, the National Centre for Scientific Research (CNRS) announced on Wednesday.
Other
Sep 18, 2013
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Whitehead Institute researchers have used the gene regulation system CRISPR/Cas to engineer mouse genomes containing reporter and conditional alleles in one step. Animals containing such sophisticated engineered alleles can ...
Cell & Microbiology
Aug 29, 2013
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By creating a powerful new gene regulation system called CRISPR-on, Whitehead Institute researchers now have the ability to increase the expression of multiple genes simultaneously and precisely manipulate each gene's expression ...
Biotechnology
Aug 27, 2013
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A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could ...
Cell & Microbiology
Aug 13, 2013
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A decade ago, gene expression seemed so straightforward: genes were either switched on or off. Not both. Then in 2006, a blockbuster finding reported that developmentally regulated genes in mouse embryonic stem cells can ...
Cell & Microbiology
Aug 11, 2013
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