Cellular stress causes cancer cell chemoresistance

There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...

Trigger of deadly food toxin discovered

(PhysOrg.com) -- A toxin produced by mold on nuts and grains can cause liver cancer if consumed in large quantities. UC Irvine researchers for the first time have discovered what triggers the toxin to form, which could lead ...

High-resolution mapping method for G4 DNA structures developed

While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...

New imaging technique can capture entire plant tissues in 3D

The cellular life inside a plant is as vibrant as the blossom. In each plant tissue—from root tip to leaf tip—there are hundreds of cell types that relay information about functional needs and environmental changes. Now, ...

Enzyme controls transport of genomic building blocks

Our DNA and its architecture are duplicated every time our cells divide. Histone proteins are key building blocks of this architecture and contain crucial information that regulates our genes. Danish researchers show how ...

Cells protect themselves against stress by keeping together

Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...

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