Last update Protein study suggests drug side effects are inevitable, 10 hours ago
A new study of both computer-created and natural proteins suggests that the number of unique pockets – sites where small molecule pharmaceutical compounds can bind to proteins – is surprisingly small, meaning drug side ...
10 hours ago
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A new study shows how complex biochemical transformations may have been possible under conditions that existed when life began on the early Earth. The study shows that RNA is capable of catalyzing electron transfer under ...
May 19, 2013
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In the race to protect society from infectious microbes, the bugs are outrunning us. The need for new therapeutic agents is acute, given the emergence of novel pathogens as well as old foes bearing heightened antibiotic resistance.
May 17, 2013
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New technology offers the promise of reducing billions of dollars of losses that occur each year from the silent, invisible killer of fruits, vegetables and cut flowers—a gas whose effects are familiar to everyone who has ...
May 15, 2013
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For 37 years, Queen's University Biochemistry professor Peter Davies has been unraveling the mystery of why some organisms including insects and fish don't freeze in the winter. His research into insect antifreeze protein ...
May 14, 2013
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(Phys.org) —3D structures of biological molecules like proteins directly affect the way they behave in our bodies. EPFL scientists have developed a new infrared-UV laser method to more accurately determine ...
May 13, 2013
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You know that summer is here when juicy red strawberries start to appear on the shelves. In Germany, this seasonal fruit has never been more popular: on average 3.5 kilos per head were consumed in 2012—a ...
May 13, 2013
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Experiments at Johns Hopkins have unearthed clues about which protein signaling molecules are allowed into hollow, hair-like "antennae," called cilia, that alert cells to critical changes in their environments.
May 12, 2013
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(Phys.org) —Researchers have made a significant first step with newly engineered biomaterials for cell transplantation that could help lead to a possible cure for Type 1 diabetes, which affects about 3 ...
May 09, 2013
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They're ba-ack! But in a new disease-fighting role. Viruses that infect and kill bacteria—used to treat infections in the pre-antibiotic era a century ago and in the former Soviet Union today—may have ...
May 08, 2013
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A team of researchers of the International School for Advanced Studies (SISSA) of Trieste and of University of Cambridge have devised a method to reduce the time used to simulate how proteins take on their ...
May 08, 2013
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Apoptosis is a programmed death mechanism that eliminates unwanted or injured cells from the body. Defects in apoptotic regulation can lead to serious physiological problems such as tissue damage or uncontrolled ...
May 08, 2013
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The trend towards automated high content assays, particularly for systems biology and drug discovery, has stimulated the development of automated fluorescence microscopy systems to image sample arrays. Today's ...
May 07, 2013
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Professor of Biochemistry Emad Tajkhorshid and colleagues have discovered that membrane transporters help not just sugars and other specific substrates cross from one side of a cellular membrane to the other—water ...
May 02, 2013
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In an advance toward solving a 50-year-old mystery, scientists are reporting new evidence on how the fluoride in drinking water, toothpastes, mouth rinses and other oral-care products prevents tooth decay. ...
May 01, 2013
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(Phys.org) —While the natural world is replete with compounds that form the basis of many disease-fighting pharmaceuticals, it is also the case that humans and other mammals produce their own host-defense ...
Apr 30, 2013
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(Phys.org) —There's hope for patients with myotonic dystrophy. A new small molecule developed by researchers at the University of Illinois has been shown to break up the protein-RNA clusters that cause ...
Apr 30, 2013
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(Phys.org) —A combined team of researchers from the U.S. and Slovenia has succeeded in creating "origami" type proteins that assemble themselves into three dimensional shapes. As a proof of concept, the ...
Apr 29, 2013
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(Phys.org) —Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn't. In the journal Angewandte Chemie, a British team has now introduced a new ...
Apr 25, 2013
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Life on Earth may have originated not in warm tropical seas, but with weird tubes of ice—sometimes called "sea stalactites"—that grow downward into cold seawater near the Earth's poles, scientists are ...
Apr 24, 2013
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In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not ...
Apr 24, 2013
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(Phys.org) —UOW chemistry researchers have revealed what turns free radicals on...and off again in an article recently published in Nature Chemistry.
Apr 23, 2013
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(Phys.org) —A Purdue University-led team has revealed the proton transfer pathway responsible for a majority of energy storage in photosynthesis. Through photosynthesis, plants, algae and bacteria convert sunlight, carbon ...
Apr 22, 2013
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Scientists at the Walter and Eliza Hall Institute and their collaborators have tailor-made a new chemical compound that blocks a protein that has been linked to poor responses to treatment in cancer patients.
Apr 21, 2013
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(Phys.org) —Water is crucial to the functioning of the body, even on very small scales. The ubiquitous liquid is key to the structure, folding and stability of proteins, but one of the still unanswered ...
Apr 19, 2013
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The journal Accounts of Chemical Research has published the article "Anion Transporters and Biological Systems", by Professor Ricardo Pérez Tomás, from the Department of Pathology and Experimental Therap ...
Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs. Adverse effects are one of the main ...
A research team from NPL and the University of Edinburgh have invented a new way to zip and unzip DNA strands using electrochemistry.
Researchers from the University of Twente's MESA+ and MIRA research institutes have succeeded in visualizing THC, the active ingredient of cannabis, in intact plant structures. The substance is mainly found in trichomes (fine ...
(Phys.org) —Scientists use scanning electron microscopes (SEMs) to study tiny structures in small organisms. SEMs can only work in a high vacuum, and exposure to such a vacuum normally causes living things ...
Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincinnati Children's Hospital ...
An international team of scientists reveals that a unique strain of potato blight they call HERB-1 triggered the Irish potato famine of the mid-19th century.
Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio, the online open-access journal of the American Society for Microb ...
(Medical Xpress)—A research team, led by Jeremy Barr, a biology post-doctoral fellow, unveils a new immune system that protects humans and animals from infection.
(Phys.org) —Entanglement, by general consensus of physicists, is the weirdest part of quantum science. To say that two particles, A and B, are entangled means that they are actually two parts of an inseparable ...
(Phys.org) —Imagine a bendable tablet computer or an electronic newspaper that could fold to fit in a pocket.
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of neurons ...
Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have ...
Parasitic wasps switch off the immune systems of fruit flies by draining calcium from the flies' blood cells, a finding that offers new insight into how pathogens break through a host's defenses.
Future teams of subterranean search and rescue robots may owe their success to the lowly fire ant, a much-despised insect whose painful bites and extensive networks of underground tunnels are all-too-familiar ...
Epidemiological studies have indicated that dietary habits and antioxidants from diet can influence the incidence of neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. In the recent years, a number ...
(Phys.org) —Newcastle University scientists have revealed the mechanism that causes a slime to form, making bacteria hard to shift and resistant to antibiotics.
A team led by David Reverter, a researcher at the Institute of Biotechnology and Biomedicine (IBB) of the UAB, has determined for the first time the three-dimensional structure of a protein pair: LC8 and ...
(Phys.org) —In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of ...
(Phys.org) —From a patient's point of view, one of the unsettling things about taking a new drug is the possibility of unwelcome side effects or worse, dangerous allergic reactions. As drugs are being developed ...
(Phys.org) —Catalysis may initiate almost all modern industrial manufacturing processes, but catalytic activity on solid surfaces is poorly understood. This is especially true for the cellulase enzymes ...
(Phys.org) —Scientists at the U.S. Department of Energy's Argonne National Laboratory, in collaboration with researchers from the Sanford-Burnham Medical Research Institute in Orlando, Fla., recently determined ...
The enzyme needed to introduce the key micronutrient selenium into bacteria looks something like a space station with 10 different docking stations.
(Phys.org) —Saratoga California high school student Eesha Khare is a co-winner of this year's Young Scientist Award sponsored by Intel. She won the award for her battery-sized supercapacitor design which ...
(Phys.org) —Herds of wooly mammoths once shook the earth beneath their feet, sending humans scurrying across the landscape of prehistoric Ohio. But then something much larger shook the Earth itself, and ...
Turns out, that old "practice makes perfect" adage may be overblown. New research led by Michigan State University's Zach Hambrick finds that a copious amount of practice is not enough to explain why people ...
These days, aerospace engineering is all about the light stuff: building airplanes with lighter wings, fuselage and landing gear in an effort to reduce fuel costs.
(Phys.org) —NASA's Mars rover Curiosity has used the drill on its robotic arm to collect a powdered sample from the interior of a rock called "Cumberland."
New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer ...
(Phys.org) —Waterproof fabrics that whisk away sweat could be the latest application of microfluidic technology developed by bioengineers at the University of California, Davis.
Meeting the demand for more data storage in smaller volumes means using materials made up of ever-smaller magnets, or nanomagnets. One promising material for a potential new generation of recording media ...
(Phys.org) —The Amazon rain forest, popularly known as the lungs of the planet, inhales carbon dioxide as it exudes oxygen. Plants use carbon dioxide from the air to grow parts that eventually fall to the ...
(Phys.org) —Enough Northwest wind energy to power about 85,000 homes each month could be stored in porous rocks deep underground for later use, according to a new, comprehensive study. Researchers at the ...
Over the past few decades, neuroscientists have made much progress in mapping the brain by deciphering the functions of individual neurons that perform very specific tasks, such as recognizing the location ...
Reinvigorated technology player Yahoo! Monday unveiled a dusted-off design of its flickr photo platform only hours after the company's dramatic acquisition of blogging site Tumblr. ...
Monday's powerful tornado in suburban Oklahoma City loosely followed the path of a killer twister that slammed the region in May 1999.
(Medical Xpress)—Individuals who learn two languages at an early age seem to switch back and forth between separate "sound systems" for each language, according to new research conducted at the University of Arizona.
The miniaturization of electronics continues to create unprecedented capabilities in computer and communications applications, enabling handheld wireless devices with tremendous computing performance operating ...
(Phys.org) —Emerging Objects, a San Francisco based fabrication studio, is pioneering the use of new kinds of material for use as an "ink" with 3-D printers. To date, their materials are based on wood, ...
A custom-built programmable 3D printer can create materials with several of the properties of living tissues, Oxford University scientists have demonstrated.
(Phys.org) —Crops aren't just for food, fiber and fuel. Researchers at the University of Florida are making new industrial applications possible for them as well.
Strong new biochemical evidence exists showing that the cereal grain sorghum is a safe food for people with celiac disease, who must avoid wheat and certain other grains, scientists are reporting. Their study, ...
(Phys.org) —Researchers at Temple University and the University of Delaware have published a study in the Journal of Biological Chemistry that sheds new light on the clotting effects of a drug that is bei ...
(Phys.org) —Vitamin C is found in many foods, and, among other things, is used to prolong shelf life. However, it is not stable in air or at room temperature. Cut fruits turn brown and the tastes of foods ...
(Phys.org) —A team of University of Pennsylvania engineers has used a pattern of nanoantennas to develop a new way of turning infrared light into mechanical action, opening the door to more sensitive infrared ...
The world's most valuable company, Apple Inc., employs a group of affiliate companies located in Ireland to avoid paying billions of dollars in U.S. income taxes, a Senate investigation has found—and its ...
Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy ...
The billion-dollar deal for Tumblr has stirred talk on the next big acquisition target in the sector, with cash-rich tech giants looking for the next potential star.
Researchers from King's College London have for the first time used a novel form of MRI to identify crucial developmental processes in the brain that are vulnerable to the effects of premature birth. This new study, published ...
Whooping cough has exploded in the United States and some other developed countries in recent decades, and many experts suspect ineffective childhood vaccines for the alarming resurgence.
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