Lighting up DNA-based nanostructures

Biophysicists from Ludwig-Maximilians-Universitaet (LMU) in Munich have used a new variant of super-resolution microscopy to visualize all the strands of a DNA-based nanostructure for the first time. The method promises to ...

Wide-field, high-resolution and broadband mesoscopic objective lens

Optical microscopes are indispensable research tools in fields such as life sciences, medical science, and materials science. The objective lens is the core component of the microscope, determining two key parameters of microscopic ...

New dye allows super-imaging of cells

A new dye might allow researchers to view natural processes in extremely small components of living cells over a prolonged period of time; a previously unattainable feat.

Study investigates crosstalk between mitochondria and lysosomes

Investigators have discovered that outer mitochondrial membrane proteins regulate crosstalk between mitochondria and lysosomes, according to a Northwestern Medicine study published in the Journal of Cell Biology. These findings ...

Student tackles labeling RNA without genetic modification

Overcoming limitations of super-resolution microscopy to optimize imaging of RNA in living cells is a key motivation for physics graduate student Takuma Inoue, who works in the lab of MIT assistant professor of physics Ibrahim ...

How blocking cell wall formation stops bacterial cell division

Researchers still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary to develop new antibiotics. And that is precisely what is urgently needed, because bacteria are currently ...

Selective cancer nanoparticle targeting under the microscope

Nanoparticles can be used as powerful vehicles to administer vaccines and prevent serious illness, as with the treatment of COVID-19 and to deliver chemotherapeutic drugs to cancer cells with goal of eradicating the cancer ...

Scientists identify novel lysosome fission factor

Lysosomes are centers for degradation, recycling, and signaling of cellular materials that are crucial for maintaining cellular homeostasis, development, and aging. To meet various physiological demands, lysosomes continuously ...

MoBIE enables modern microscopy with massive data sets

High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination of such large imaging data sets poses significant ...

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