Chemists tackle the tough challenge of recycling mixed plastics
Plastics are everywhere in our daily lives, but not all plastics are created equal—far from it.
Polymers
Apr 26, 2023
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Page 11 - News tagged with small molecules
A fast and efficient method for detecting microRNAs
In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes. This marked the discovery of microRNAs (miRNAs), which are now ...
Cell & Microbiology
Apr 24, 2023
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A potential treatment for multidrug-resistant bacteria
A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications. Instead of targeting the bacteria directly, the drug blocks key toxins involved in the ...
Cell & Microbiology
Apr 18, 2023
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The paradox of thrombosis: Determining how hibernating bears and paraplegics avoid blood clots
Bears in hibernation as well as paraplegic people spend months or even years lying almost motionless while avoiding dangerous blood clots. In healthy people, however, being bedridden is always accompanied by the risk of thrombosis—a ...
Molecular & Computational biology
Apr 14, 2023
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Computer simulations deepen our understanding of how drugs get into the blood
There is a need for new drugs. For example, many of the antibiotics that we have been using for a long time are becoming less effective. Chemists and pharmaceutical scientists are frantically searching for new active substances, ...
Biochemistry
Apr 13, 2023
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A novel database aimed at promoting drug design using cyclic peptides
CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising compounds. This database was ...
Biochemistry
Apr 5, 2023
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New RNA-based toolkit to regulate gene activity could advance regenerative medicine, gene therapy and biotechnology
The Okinawa Institute of Science and Technology (OIST), in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately ...
Biotechnology
Mar 30, 2023
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Discovery of drug candidate that neutralizes SARS-CoV-2 could reduce length of infection upon exposure
The discovery of a small molecule in the research lab of Bradley McConnell, professor of pharmacology at the University of Houston College of Pharmacy, may well be the genesis of new medication which could shorten the course ...
Biochemistry
Mar 28, 2023
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Hidden metabolite–protein interactions captured by MIDAS
A research group of 46, led by the University of Utah School of Medicine, reports an innovative new method to analyze 33 enzymes from human carbohydrate metabolism and identify 830 protein-metabolite interactions, including ...
Using peptides instead of DNA to tag molecules to speed up drug discovery
A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
