Genomic regulatory map of the zebrafish

Zebrafish and humans look very different on the outside. Yet about 70 percent of their genes are similar to human genes—including many that can trigger diseases. That makes the animal a popular model organism. Many observations ...

Predatory phytoplankton key to understanding ocean ecosystem

A team of researchers has spent years taming mysterious marine microbes from the open ocean to grow in a lab, to investigate their feeding habits. The group's latest discoveries, led by University of Hawai'i at Mānoa oceanography ...

DisCo: Boosting the efficiency of single-cell RNA sequencing

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population—which is virtually how all cells exist in the ...

Probing how proteins pair up inside cells

Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of which interact with partner ...

Modeling how cells choose their fates

It may seem hard to believe, but each one of us began as a single cell that proliferated into the trillions of cells that make up our bodies. Though each of our cells has the exact same genetic information, each also performs ...

Unprecedented cellular maps of tissues enabled by new tool

The study of the human body at single-cell level has received a boost with the creation of a new tool, which will allow researchers to see not only the function of cells, but also where they are situated within tissues. The ...

Pioneering new technique to barcode cells

Scientists have developed a pioneering new technique to barcode individual cells more accurately and efficiently—which could help pave the way for quicker disease diagnosis. 

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