A team of physicists working at the intersection of theory and experiment are shedding new light on the "teamwork" of molecular motors—called RNA polymerases (RNAPs)—that mediate DNA transcription. During transcription, ...
General Physics
Dec 9, 2021
1
35
While investigating the unusual G quadruplex DNA structure (G4), the Simon Elsässer group has developed a more accurate method for mapping these structures in the genome. G4 CUT&Tag revealed numerous G4s in the human and ...
Biotechnology
Dec 6, 2021
0
52
The ability to edit the genome by altering the DNA sequence inside a living cell is powerful for research and holds enormous promise for the treatment of diseases. However, existing genome editing technologies frequently ...
Biotechnology
Oct 20, 2021
0
48
More than 2 billion people worldwide are fully vaccinated against COVID-19. However, many who live in resource-limited countries haven't been able to get vaccines, partly because these areas lack temperature-controlled shipping ...
Bio & Medicine
Sep 22, 2021
1
3061
Researchers at McMaster University have developed a sophisticated new tool that could help provide early warning of rare and unknown viruses in the environment and identify potentially deadly bacterial pathogens which cause ...
Biotechnology
Sep 15, 2021
0
188
In their search for pink river dolphins, researchers in the Peruvian Amazon scooped up river water sloshing with genetic material that they hoped could trace the elusive creatures.
Ecology
Sep 7, 2021
0
110
Getting a full understanding of how genes are regulated is a major goal of scientists worldwide. Now, a Florida State University professor and his research partners have developed a technique that can map out nearly all of ...
Biotechnology
Aug 13, 2021
1
478
Scientists have used CRISPR gene-editing technology to successfully block the transmission of the SARS-CoV-2 virus in infected human cells, according to research released Tuesday that could pave the way for COVID-19 treatments.
Biotechnology
Jul 13, 2021
0
978
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
0
30
Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) show signs that they are preserved by natural selection. When G4s are located in the regulatory ...
Molecular & Computational biology
Jun 29, 2021
1
139
