Aging cells lose their grip on DNA rogues

(Phys.org)—Transposable elements are mobile strands of DNA that insert themselves into chromosomes with mostly harmful consequences. Cells try to keep them locked down, but in a new study, Brown University researchers ...

Researchers discover mechanism that limits scar formation

Researchers from the University of Illinois at Chicago have discovered that an unexpected cellular response plays an important role in breaking down and inhibiting the formation of excess scar tissue in wound healing.

Aging-emulating biosystem derived from hTSCs

A research team from the Center for Translational Stem Cell Biology (CTSCB) under the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has developed the world's first cellular system that can be used to rapidly ...

Fountain of youth for plants: E3 ligase's role in leaf longevity

A recent study uncovers the intricate molecular mechanisms that regulate leaf senescence in apple plants, focusing on the crucial role of the E3 ligase enzyme, MdPUB23, and its interaction with the ABI5 protein. This research ...

Apple preharvest drop not linked to xylem functionality

Heat stress induces and accelerates leaf senescence, which is characterized by a loss of chlorophyll and cellular membrane deterioration, as well as oxidative damage). Leaf senescence can be exacerbated by the hormone ethylene, ...

A zebrafish model of senescence for rapid testing

Senescence (the process of growing old) drives the onset and severity of multiple aging-associated diseases and frailty. As a result, there has been an increased interest in mechanistic studies and the search for compounds ...

Phthalate alternative may harm brain development and health

Growing concerns over the potential health effects of exposure to phthalates, a component of many plastics and also known as a plasticizer, have led to a search for safer alternatives. In a new study conducted in cell cultures, ...

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