Sequencing messenger RNA molecules from individual cells offers a glimpse into the lives of those cells, revealing what they're doing at a particular time. However, the equipment required to do this kind of analysis is cumbersome ...
Biotechnology
Feb 13, 2017
0
7
Small molecules of RNA (tens to hundreds of nucleotides in length) play a key regulatory role in bacteria. Due to their small size, directly measuring the number of small RNA (sRNA) present in a single bacterium has proven ...
Analytical Chemistry
Jun 18, 2013
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0
Pioneering new research could offer a fascinating new insight into how genomic information is read.
Biotechnology
Feb 12, 2018
2
30
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...
Cell & Microbiology
Dec 22, 2011
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0
Embryonic stem cells (ESCs) retain their ability to self-renew indefinitely thanks to a number of proteins known as pluripotency factors. These factors must be modified at the RNA level before they are turned into proteins ...
Cell & Microbiology
Jan 29, 2014
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0
A novel approach developed at the Friedrich Miescher Institute for Biomedical Research (FMI) has allowed scientists in Dirk Schübeler's group to dissect and quantify the individual steps of transcription initiation. Unexpectedly, ...
Cell & Microbiology
Jul 26, 2017
0
15
Researchers led by Mustafa Khammash have developed a new method that uses blue light to control the transcription of DNA into RNA in single cells. The technology could also be used in tissue engineering and stem cell research.
Cell & Microbiology
Oct 17, 2018
0
50
The basic process of life, known as transcription, is the process by which the genetic information stored in DNA is copied by specific enzymes called RNA polymerases into RNA molecules. Despite a huge progress in our understanding ...
Molecular & Computational biology
Feb 21, 2022
0
39
Control of RNA lifespan is vital for the proper functioning of our cells. Marc Bühler's group at the Friedrich Miescher Institute for Biomedical Research (FMI) has discovered a novel mechanism determining the fate of RNA ...
Cell & Microbiology
Jun 5, 2017
0
12
One of the most successful techniques to combat multidrug resistance in cancer cells is the downregulation of those genes responsible for drug resistance. Chinese scientists have now developed a nanoplatform that selectively ...
Biochemistry
Nov 21, 2018
0
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