Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository ...
Molecular & Computational biology
Jun 11, 2021
39
12351
The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed.
Cell & Microbiology
Jul 3, 2015
72
5312
How did life begin on Earth and could it exist elsewhere? Researchers at Simon Fraser University have isolated a genetic clue—an enzyme known as an RNA polymerase—that provides new insights about the origins of life. ...
Evolution
Mar 19, 2021
25
6444
New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now—precisely how the copying of genetic material that, once started, is properly turned ...
Cell & Microbiology
Nov 26, 2020
8
1789
An international team of scientists has recently developed a novel type of nano engine made of DNA. It is driven by a clever mechanism and can perform pulsing movements. The researchers are now planning to fit it with a coupling ...
Bio & Medicine
Oct 19, 2023
0
793
Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...
Biotechnology
Apr 21, 2011
0
0
A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.
Biotechnology
Feb 9, 2024
0
286
A duo of scientists at Penn State University has achieved a major milestone in understanding how genomic "dark matter" originates. This "dark matter"—called non-coding RNA—does not contain the blueprint for making proteins ...
Biotechnology
Sep 18, 2013
12
1
Scientists from Rutgers University-New Brunswick, the biotechnology company NAICONS Srl., and elsewhere have discovered a new antibiotic effective against drug-resistant bacteria: pseudouridimycin. The new antibiotic is produced ...
Cell & Microbiology
Jun 15, 2017
0
672
In a new Nature Communications study, researchers have explored the construction of genetic circuits on single DNA molecules, demonstrating localized protein synthesis as a guiding principle for dissipative nanodevices, offering ...
RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses. In chemical terms, RNAP is a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript.
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