Bacteria are nearly ubiquitous and have tremendous impacts on human and ecological health. And yet, they remain largely mysterious to us. Princeton MOL faculty Zemer Gitai, Britt Adamson and Ned Wingreen launched a joint ...
Cell & Microbiology
Sep 14, 2023
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20
Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes. These enzymes are growing increasingly common, appearing worldwide ...
Biotechnology
Aug 14, 2023
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8
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic ...
Cell & Microbiology
Aug 8, 2023
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5
The mechanisms of RNA-binding proteins (RBPs)-mediated post-transcriptional regulation of pre-existing mRNAs, which is essential for spermatogenesis, remain poorly understood.
Cell & Microbiology
Jul 25, 2023
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1
The human body consists of trillions of cells, and 60% of the energy used within a cell is dedicated to a specific molecular machine. That machine is responsible for producing proteins, which are fundamental building blocks ...
Cell & Microbiology
Jul 21, 2023
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22
Life runs on ribosomes. Every cell on Earth needs ribosomes to translate genetic information into all the proteins needed for the organism to function—and to in turn make more ribosomes. But scientists still lack a clear ...
Cell & Microbiology
Jul 6, 2023
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402
All biological processes in our cells are constantly monitored to prevent the accumulation of defective proteins. In the worst case, such protein clumps can trigger diseases. The synthesis of new proteins is particularly ...
Cell & Microbiology
Jun 20, 2023
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248
Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals—from fuels to fabrics and drugs—beyond the normal repertoire of microbes.
Biochemistry
Jun 13, 2023
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555
Scientists at the University of Illinois Chicago have found that a peptide from fruit flies could lead to new antibiotics.
Cell & Microbiology
Jun 6, 2023
0
38
In a discovery fundamental to the inner workings of cells, scientists have discovered that if oxidative stress damages protein factories called ribosomes, repair crews may move in to help fix the damage so work can quickly ...
Cell & Microbiology
Apr 21, 2023
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