A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.
Biotechnology
Feb 21, 2022
0
132
In a text file, the rows of letters A, T, C and G appearing over and over in a dizzying array of combinations, are unremarkable, save perhaps for the absence of all the other letters of the alphabet. Yet the specific sequence ...
Molecular & Computational biology
Nov 26, 2021
0
17
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
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30
Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called G-quadruplexes (G4s) show signs that they are preserved by natural selection. When G4s are located in the regulatory ...
Molecular & Computational biology
Jun 29, 2021
1
139
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
Biotechnology
Dec 1, 2020
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29
A new study from Michigan State University makes inroads in learning to "read" the genome, a key goal of modern biology.
Biotechnology
May 9, 2016
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37
It is easy to distinguish a mouse from a cow. But for members of the same class of mammal, where do such differences begin? In 2011, scientists discovered there were differences in cow and mice blastocysts, the tiny hollow ...
Biotechnology
Feb 23, 2015
2
47
Thousands of sequences that control genes are active in the developing human limb and may have driven the evolution of the human hand and foot, a comparative genomics study led by Yale School of Medicine researchers has found
Biotechnology
Jul 3, 2013
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0
(Phys.org) —A Cornell study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play roles in turning genes ...
Biotechnology
Jun 12, 2013
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0
Architect genes are responsible for organizing structures of the body during embryonic development. Some of them, namely the Hox genes, are involved in the formation of forelimbs. They are activated in two successive waves, ...
Biotechnology
Jun 6, 2013
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