When it comes to drug development, membrane proteins play a crucial role, with about 50% of drugs targeting these molecules. Understanding the function of these membrane proteins, which connect to the membranes of cells, ...
Cell & Microbiology
Feb 8, 2024
0
39
Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages. A vital step in protein-coding gene expression is messenger RNA (mRNA) export, which involves ...
Cell & Microbiology
Feb 8, 2024
0
15
Ubiquitin ligases regulate many processes in living cells. Depending on how many ubiquitin molecules they attach to the target proteins and in which way, they control the protein's fate.
Cell & Microbiology
Feb 8, 2024
0
1
A research team from the Department of Chemistry at the Universität Hamburg has succeeded for the first time in identifying at the molecular level the dynamic mechanism used by the enzyme RNase R to degrade the ribosomal ...
Biochemistry
Feb 8, 2024
0
5
Organogenesis, an important aspect of flowering, helps reveal key processes of plant development such as the formation of floral organs, attainment of reproductive capability, and abscission leading to seed and fruit development.
Plants & Animals
Feb 7, 2024
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2
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. ...
Cell & Microbiology
Feb 5, 2024
0
73
A study at the University of Cologne's CECAD Cluster of Excellence in Aging Research has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. ...
Cell & Microbiology
Feb 2, 2024
0
102
Researchers at ETH Zurich recently developed highly realistic simulations of the proteins on sperm and egg cells coupling together before they fuse. These findings enabled the research team to solve several mysteries of fertilization ...
Molecular & Computational biology
Feb 2, 2024
0
18
The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method ...
Cell & Microbiology
Feb 1, 2024
0
1
Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function. This dogma is challenged ...
Molecular & Computational biology
Jan 31, 2024
0
27
