New method for marking neurotransmitter receptors in living animal brains
Researchers have developed a new method of labeling naïve neurotransmitter receptor proteins in living animal brains.
Researchers have developed a new method of labeling naïve neurotransmitter receptor proteins in living animal brains.
Biochemistry
Feb 22, 2024
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32
A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.
Biochemistry
Feb 21, 2024
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16
Above ground, plants stretch toward the sun. Below ground, plants tunnel through the earth. As roots soak up water and nutrients from surrounding soil, they grow and stretch to develop distinct root system architectures. ...
Molecular & Computational biology
Feb 14, 2024
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99
Penn Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases ...
Biotechnology
Feb 8, 2024
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55
Ubiquitin ligases regulate many processes in living cells. Depending on how many ubiquitin molecules they attach to the target proteins and in which way, they control the protein's fate.
Cell & Microbiology
Feb 8, 2024
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1
Northwestern University researchers have developed the first selective therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.
Bio & Medicine
Jan 16, 2024
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27
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
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66
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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57
Exploring the biomedical interactions for chemical compounds and protein targets is crucial for drug discovery. Determining these drug–drug interactions (DDI) and drug–target interactions (DTI) not only reveals the potential ...
Molecular & Computational biology
Dec 5, 2023
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23
The idea of irreversible inhibitors adhering permanently to a target protein has gained increasing attention for application in potential drug development. However, one of many hurdles is the possibility of protein mutations ...
Biochemistry
Nov 29, 2023
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20